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Cdk13 cyclin-dependent kinase 13 [ Mus musculus (house mouse) ]

Gene ID: 69562, updated on 8-May-2016
Official Symbol
Cdk13provided by MGI
Official Full Name
cyclin-dependent kinase 13provided by MGI
Primary source
MGI:MGI:1916812
See related
Ensembl:ENSMUSG00000041297
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cdc2l5; 2310015O17Rik
Orthologs
Location:
13; 13 A3.1
Exon count:
16
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 13 NC_000079.6 (17715962..17805332, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (17807796..17896931, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene succinyl-CoA glutarate-CoA transferase Neighboring gene predicted gene, 40826 Neighboring gene M-phase specific PLK1 intereacting protein Neighboring gene microRNA 466i Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene ADP-ribosylation factor 3 pseudogene Neighboring gene v-ral simian leukemia viral oncogene A (ras related)

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II carboxy-terminal domain kinase activity ISO
Inferred from Sequence Orthology
more info
 
cyclin binding IPI
Inferred from Physical Interaction
more info
PubMed 
cyclin binding ISO
Inferred from Sequence Orthology
more info
 
cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
alternative mRNA splicing, via spliceosome IDA
Inferred from Direct Assay
more info
PubMed 
hemopoiesis ISO
Inferred from Sequence Orthology
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
phosphorylation of RNA polymerase II C-terminal domain ISO
Inferred from Sequence Orthology
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
cyclin K-CDK13 complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
nuclear cyclin-dependent protein kinase holoenzyme complex IDA
Inferred from Direct Assay
more info
PubMed 
nuclear speck ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
cyclin-dependent kinase 13
Names
CDC2-related protein kinase 5
cell division cycle 2-like 5 (cholinesterase-related cell division controller)
cell division cycle 2-like protein kinase 5
cell division protein kinase 13
NP_001074527.1
NP_081394.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081058.2NP_001074527.1  cyclin-dependent kinase 13 isoform 1

    See identical proteins and their annotated locations for NP_001074527.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC154219, AC154828
    Consensus CDS
    CCDS36604.1
    UniProtKB/Swiss-Prot
    Q69ZA1
    Related
    ENSMUSP00000036013, ENSMUST00000042365
    Conserved Domains (2) summary
    smart00220
    Location:705994
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:697998
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12
  2. NM_027118.1NP_081394.1  cyclin-dependent kinase 13 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.
    Source sequence(s)
    AC154219, AC154828
    UniProtKB/Swiss-Prot
    Q69ZA1
    Conserved Domains (2) summary
    smart00220
    Location:705994
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:697998
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p3 C57BL/6J

    Range
    17715962..17805332 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244344.1XP_011242646.1  

    Conserved Domains (2) summary
    smart00220
    Location:91380
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:83384
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12
  2. XM_006516767.2XP_006516830.1  

    Conserved Domains (2) summary
    smart00220
    Location:705994
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:697998
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12
  3. XM_006516766.2XP_006516829.1  

    Conserved Domains (2) summary
    smart00220
    Location:705994
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:697998
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

Alternate Mm_Celera

Genomic

  1. AC_000035.1 Alternate Mm_Celera

    Range
    18019147..18109011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)