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Hspb2 heat shock protein 2 [ Mus musculus (house mouse) ]

Gene ID: 69253, updated on 8-May-2016
Official Symbol
Hspb2provided by MGI
Official Full Name
heat shock protein 2provided by MGI
Primary source
MGI:MGI:1916503
See related
Ensembl:ENSMUSG00000038086
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MKBP; 27kDa; HSP27; 2810021G24Rik
Orthologs
Location:
9 A5.3; 9 27.75 cM
Exon count:
2
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (50751072..50752354, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (50559177..50560459, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene DIX domain containing 1 Neighboring gene predicted gene, 39337 Neighboring gene RIKEN cDNA 2310030G06 gene Neighboring gene RIKEN cDNA 1110032A03 gene Neighboring gene crystallin, alpha B Neighboring gene ferredoxin-fold anticodon binding domain containing 1 Neighboring gene predicted gene, 38476

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
    Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
  • Epstein-Barr virus infection, conserved biosystem (from KEGG)
    Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
  • MAPK signaling pathway, organism-specific biosystem (from WikiPathways)
    MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • Proteoglycans in cancer, organism-specific biosystem (from KEGG)
    Proteoglycans in cancer, organism-specific biosystemMany proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that contribute to biology of various types of cancer including proliferation, adhesion, angiogenesis a...
  • Proteoglycans in cancer, conserved biosystem (from KEGG)
    Proteoglycans in cancer, conserved biosystemMany proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that contribute to biology of various types of cancer including proliferation, adhesion, angiogenesis a...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
structural constituent of eye lens IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
response to heat ISO
Inferred from Sequence Orthology
more info
 
somatic muscle development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
heat shock protein beta-2
Names
heat shock 27kD protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164708.1NP_001158180.1  heat shock protein beta-2 isoform 2

    See identical proteins and their annotated locations for NP_001158180.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site, compared to variant 1. The resulting protein (isoform 2) is missing an internal segment when it is compared to isoform 1.
    Source sequence(s)
    AK012780, BU704695
    UniProtKB/Swiss-Prot
    Q99PR8
    Conserved Domains (1) summary
    cl00175
    Location:3254
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
  2. NM_024441.3NP_077761.3  heat shock protein beta-2 isoform 1

    See identical proteins and their annotated locations for NP_077761.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
    Source sequence(s)
    AK012780, BC064051, BU704695
    Consensus CDS
    CCDS23171.1
    UniProtKB/Swiss-Prot
    Q99PR8
    UniProtKB/TrEMBL
    Q6P3C8
    Related
    ENSMUSP00000042374, ENSMUST00000042790
    Conserved Domains (1) summary
    cl00175
    Location:67148
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    50751072..50752354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    48038238..48039519 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)