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Phkg2 phosphorylase kinase, gamma 2 (testis) [ Mus musculus (house mouse) ]

Gene ID: 68961, updated on 8-May-2016
Official Symbol
Phkg2provided by MGI
Official Full Name
phosphorylase kinase, gamma 2 (testis)provided by MGI
Primary source
MGI:MGI:1916211
See related
Ensembl:ENSMUSG00000030815 Vega:OTTMUSG00000026244
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500017I02Rik
Orthologs
Location:
7; 7 F4
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 7 NC_000073.6 (127573344..127583307)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134716862..134726821)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene Snf2-related CREBBP activator protein Neighboring gene small nucleolar RNA, H/ACA box 30 Neighboring gene transmembrane protein 265 Neighboring gene coiled-coil domain containing 189 Neighboring gene ring finger protein 40 Neighboring gene RIKEN cDNA 1700120K04 gene

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Calcium signaling pathway, organism-specific biosystem (from KEGG)
    Calcium signaling pathway, organism-specific biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Calcium signaling pathway, conserved biosystem (from KEGG)
    Calcium signaling pathway, conserved biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Glucagon signaling pathway, organism-specific biosystem (from KEGG)
    Glucagon signaling pathway, organism-specific biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • Glucagon signaling pathway, conserved biosystem (from KEGG)
    Glucagon signaling pathway, conserved biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • Glucose metabolism, organism-specific biosystem (from REACTOME)
    Glucose metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Glycogen Metabolism, organism-specific biosystem (from WikiPathways)
    Glycogen Metabolism, organism-specific biosystemGlycogen is a very large, branched polymer of glucose residues. Within skeletal musle and liver glucose is stored as glycogen. In the liver, glycogen synthesis and degradation are regulated to mainta...
  • Glycogen breakdown (glycogenolysis), organism-specific biosystem (from REACTOME)
    Glycogen breakdown (glycogenolysis), organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Insulin signaling pathway, organism-specific biosystem (from KEGG)
    Insulin signaling pathway, organism-specific biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
  • Insulin signaling pathway, conserved biosystem (from KEGG)
    Insulin signaling pathway, conserved biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
  • Metabolism, organism-specific biosystem (from REACTOME)
    Metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Metabolism of carbohydrates, organism-specific biosystem (from REACTOME)
    Metabolism of carbohydrates, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphorylase kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
phosphorylase kinase complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
phosphorylase b kinase gamma catalytic chain, liver/testis isoform
Names
PHK-gamma-LT
PHK-gamma-T
phosphorylase b kinase gamma catalytic chain, testis/liver isoform
phosphorylase kinase subunit gamma-2
serine/threonine-protein kinase PHKG2
NP_081164.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026888.3NP_081164.2  phosphorylase b kinase gamma catalytic chain, liver/testis isoform

    See identical proteins and their annotated locations for NP_081164.2

    Status: VALIDATED

    Source sequence(s)
    AA198694, AK005277, AK079680, BQ176174
    Consensus CDS
    CCDS21869.1
    UniProtKB/Swiss-Prot
    Q9DB30
    Related
    ENSMUSP00000033086, OTTMUSP00000032276, ENSMUST00000033086, OTTMUST00000064904
    Conserved Domains (2) summary
    smart00220
    Location:24291
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:13291
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p3 C57BL/6J

    Range
    127573344..127583307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508167.2XP_006508230.1  

    See identical proteins and their annotated locations for XP_006508230.1

    UniProtKB/Swiss-Prot
    Q9DB30
    Conserved Domains (2) summary
    smart00220
    Location:24291
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:13291
    PKc_like; Protein Kinases, catalytic domain
  2. XM_006508168.1XP_006508231.1  

    See identical proteins and their annotated locations for XP_006508231.1

    Conserved Domains (2) summary
    smart00220
    Location:13194
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:10194
    PKc_like; Protein Kinases, catalytic domain
  3. XM_006508169.2XP_006508232.1  

    See identical proteins and their annotated locations for XP_006508232.1

    Conserved Domains (2) summary
    smart00220
    Location:13194
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:10194
    PKc_like; Protein Kinases, catalytic domain
  4. XM_006508172.2XP_006508235.1  

    See identical proteins and their annotated locations for XP_006508235.1

    Conserved Domains (2) summary
    smart00220
    Location:1182
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:1182
    PKc_like; Protein Kinases, catalytic domain
  5. XM_006508170.1XP_006508233.1  

    See identical proteins and their annotated locations for XP_006508233.1

    Conserved Domains (2) summary
    smart00220
    Location:1189
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:1189
    PKc_like; Protein Kinases, catalytic domain
  6. XM_011241891.1XP_011240193.1  

    See identical proteins and their annotated locations for XP_011240193.1

    UniProtKB/Swiss-Prot
    Q9DB30
    Related
    ENSMUSP00000113533, OTTMUSP00000036432, ENSMUST00000121004, OTTMUST00000071200
    Conserved Domains (2) summary
    smart00220
    Location:24291
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:13291
    PKc_like; Protein Kinases, catalytic domain
  7. XM_006508171.1XP_006508234.1  

    See identical proteins and their annotated locations for XP_006508234.1

    Conserved Domains (2) summary
    smart00220
    Location:1189
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:1189
    PKc_like; Protein Kinases, catalytic domain

Alternate Mm_Celera

Genomic

  1. AC_000029.1 Alternate Mm_Celera

    Range
    127418345..127428215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)