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Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 [ Mus musculus (house mouse) ]

Gene ID: 68916, updated on 8-May-2016
Official Symbol
Cdkal1provided by MGI
Official Full Name
CDK5 regulatory subunit associated protein 1-like 1provided by MGI
Primary source
MGI:MGI:1921765
See related
Ensembl:ENSMUSG00000006191 Vega:OTTMUSG00000000663
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1190005B03Rik; 6620401C13Rik
Orthologs
Location:
13; 13 A3.3
Exon count:
22
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 13 NC_000079.6 (29191751..29855684, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (29417175..29947457, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A330102I10 gene Neighboring gene predicted gene, 34747 Neighboring gene predicted gene, 34899 Neighboring gene E2F transcription factor 3 Neighboring gene predicted gene, 40860

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
4 iron, 4 sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
 
N6-threonylcarbomyladenosine methylthiotransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
N6-threonylcarbomyladenosine methylthiotransferase activity ISO
Inferred from Sequence Orthology
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
RNA modification IEA
Inferred from Electronic Annotation
more info
 
macromolecule modification IEA
Inferred from Electronic Annotation
more info
 
maintenance of translational fidelity IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA methylthiolation IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
rough endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
threonylcarbamoyladenosine tRNA methylthiotransferase
Names
CDK5 regulatory subunit-associated protein 1-like 1
tRNA-t(6)A37 methylthiotransferase
NP_653119.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308486.1NP_001295415.1  threonylcarbamoyladenosine tRNA methylthiotransferase isoform 2

    See identical proteins and their annotated locations for NP_001295415.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks multiple alternate 3' exons and contains two alternate 3' exons, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK045506, AL513025
    UniProtKB/Swiss-Prot
    Q91WE6
    Conserved Domains (1) summary
    pfam00919
    Location:6494
    UPF0004; Uncharacterized protein family UPF0004
  2. NM_144536.3NP_653119.1  threonylcarbamoyladenosine tRNA methylthiotransferase isoform 1

    See identical proteins and their annotated locations for NP_653119.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK004490, AK045506, AK082629, AL513025, AL589701, DV651111
    Consensus CDS
    CCDS26412.1
    UniProtKB/Swiss-Prot
    Q91WE6
    Related
    ENSMUSP00000006353, OTTMUSP00000000607, ENSMUST00000006353, OTTMUST00000001282
    Conserved Domains (3) summary
    cd01335
    Location:207410
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
    pfam00919
    Location:64145
    UPF0004; Uncharacterized protein family UPF0004
    TIGR01578
    Location:64491
    MiaB-like-B; MiaB-like tRNA modifying enzyme, archaeal-type

RNA

  1. NR_131896.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate 3' exon and contains two alternate 3' exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK082629, AL513025

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p3 C57BL/6J

    Range
    29191751..29855684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516763.2XP_006516826.1  

    See identical proteins and their annotated locations for XP_006516826.1

    Conserved Domains (1) summary
    smart00729
    Location:7123
    Elp3; Elongator protein 3, MiaB family, Radical SAM
  2. XM_006516762.2XP_006516825.1  

    Conserved Domains (1) summary
    smart00729
    Location:6170
    Elp3; Elongator protein 3, MiaB family, Radical SAM
  3. XM_006516764.2XP_006516827.1  

    See identical proteins and their annotated locations for XP_006516827.1

    Conserved Domains (1) summary
    smart00729
    Location:7123
    Elp3; Elongator protein 3, MiaB family, Radical SAM
  4. XM_011244342.1XP_011242644.1  

    Conserved Domains (3) summary
    cd01335
    Location:207410
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
    pfam00919
    Location:64145
    UPF0004; Uncharacterized protein family UPF0004
    pfam04055
    Location:207380
    Radical_SAM; Radical SAM superfamily

RNA

  1. XR_382070.2 RNA Sequence

    Related
    ENSMUST00000140278, OTTMUST00000074831

Alternate Mm_Celera

Genomic

  1. AC_000035.1 Alternate Mm_Celera

    Range
    29544145..30074351 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)