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    STRN striatin, calmodulin binding protein [ Homo sapiens ]

    Gene ID: 6801, updated on 26-Jan-2012

    Summary

    Official Symbol
    STRNprovided by HGNC
    Official Full Name
    striatin, calmodulin binding proteinprovided by HGNC
    Primary source
    HGNC:11424
    See related
    Ensembl:ENSG00000115808; HPRD:18124; Vega:OTTHUMG00000100959
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SG2NA

    Genomic context

    Location :
    2p22.2
    Sequence :
    Chromosome: 2; NC_000002.11 (37064841..37193615, complement)
    See STRN in Epigenomics, MapViewer

    Chromosome 2 - NC_000002.11Genomic Context describing neighboring genes Neighboring gene guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 pseudogene Neighboring gene vitrin Neighboring gene HEAT repeat containing 5B Neighboring gene coiled-coil domain containing 75

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    O43815 Activating transcription factor 7 interacting protein ATF7IP    HPRD  PubMed  
    O43815 Calmodulin 1 CALM1    HPRD  PubMed  
    O43815 Q03135 CAV1    HPRD  PubMed  
    O43815 P03372 ESR1    HPRD  PubMed  
    O43815 P63096 GNAI1    HPRD  PubMed  
    O43815 Protein phosphatase 2A, catalytic subunit, alpha isoform PPP2CA    HPRD  PubMed  
    O43815 P30153 PPP2R1A    HPRD  PubMed  
    O43815 P30154 PPP2R1B    HPRD  PubMed  
    BioGRID:112674 BioGRID:115827 CCT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:113054 CCT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:115826 CCT4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:116603 CCT5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:107346 CCT6A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:115932 CCT6B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:115825 CCT7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:115933 CCT8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:123842 CTTNBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:121000 CTTNBP2NL    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:207994 Dynll1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:124497 FAM40A    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:121534 FAM40B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:117566 FGFR1OP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:110333 MCC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:117369 MOB4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:119722 MST4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:116400 PDCD10    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:111507 PPP2CA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:111508 PPP2CB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:111510 PPP2R1A    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:111511 PPP2R1B    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:123136 SIKE1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:113620 SLMAP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:114011 STK24    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:115757 STK25    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:118999 STRN3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:118941 STRN4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:112810 TCP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:112674 BioGRID:123249 TRAF3IP3    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:112674 BioGRID:120139 ZRANB1    BioGRID  PubMed Affinity Capture-MS 

    General gene information

    Markers

    Homology

    Pathways from BioSystems

    Clone Names

    • MGC125642

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    armadillo repeat domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    calmodulin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    calmodulin binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    estrogen receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphatase 2A binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    Wnt receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dendrite development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    locomotory behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    tight junction assembly NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    dendritic spine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    neuronal cell body ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    postsynaptic density ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    postsynaptic membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein complex IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with protein phosphatase type 2A complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    tight junction IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    striatin
    Names
    striatin
    striatin, calmodulin-binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_003162.3NP_003153.2  striatin

      Status: VALIDATED

      Source sequence(s)
      AC007382, AJ223814, AK026934
      Consensus CDS
      CCDS1784.1
      UniProtKB/Swiss-Prot
      O43815
      Related
      ENSP00000263918, OTTHUMP00000126951, ENST00000263918, OTTHUMT00000218568
      Conserved Domains (2) summary
      cd00200
      Location:455779
      Blast Score: 515
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:48181
      Blast Score: 474
      Striatin; Striatin family

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000002.11 Reference GRCh37.p5 Primary Assembly

      Range
      37064841..37193615, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000134.1 Alternate HuRef

      Range
      36805145..36933870, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC007382.3 AAF66162.1
    genomic AC007404.4 AAY24273.1
    genomic CH471053.2 EAX00414.1
    mRNA AJ223814.1 CAA11560.1
    mRNA AK026934.1 None
    mRNA AK307836.1 None
    mRNA BC015406.1 None
    mRNA BC036416.1 None
    mRNA BC106878.2 AAI06879.1
    mRNA BC106879.2 AAI06880.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    O43815.4 GenPept UniProtKB/Swiss-Prot:O43815
    Q3B874 GenPept UniProtKB/TrEMBL:Q3B874

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