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CLEC7A C-type lectin domain containing 7A [ Ovis aries (sheep) ]

Gene ID: 678685, updated on 5-Mar-2024

Summary

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Gene symbol
CLEC7A
Gene description
C-type lectin domain containing 7A
See related
EnsemblRapid:ENSOARG00020000464
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (205356448..205389499)

Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 52B Neighboring gene oxidized low density lipoprotein receptor 1 Neighboring gene C-type lectin domain family 1 member A Neighboring gene C-type lectin domain containing 9A Neighboring gene C-type lectin domain family 1 member B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Variation in the ovine C-type lectin dectin-1 gene (CLEC7A). Zhou H, et al. Dev Comp Immunol, 2010 Mar. PMID 19914281
  2. Differential expression of pattern recognition receptors in sheep tissues and leukocyte subsets. Nalubamba KS, et al. Vet Immunol Immunopathol, 2007 Aug 15. PMID 17604125

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. variation in exons 4-6 of the ovine dectin-1 gene (CLEC7A) was investigated
    Title: Variation in the ovine C-type lectin dectin-1 gene (CLEC7A).
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables (1->3)-beta-D-glucan binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pattern recognition receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to molecule of fungal origin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in detection of fungus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in detection of molecule of fungal origin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phagocytosis, recognition IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytokine production involved in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of killing of cells of another organism IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of lymphocyte activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
C-type lectin domain family 7 member A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    205356448..205389499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042247545.2 → XP_042103479.1  C-type lectin domain family 7 member A isoform X1

    UniProtKB/TrEMBL
    W5QIN1
    Related
    ENSOARP00020000495.2, ENSOART00020000624.2
    Conserved Domains (1) summary
    cd03593
    Location:119 → 242
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

  2. XM_042247546.2 → XP_042103480.1  C-type lectin domain family 7 member A isoform X1

    UniProtKB/TrEMBL
    W5QIN1
    Conserved Domains (1) summary
    cd03593
    Location:119 → 242
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

  3. XM_042247548.2 → XP_042103482.1  C-type lectin domain family 7 member A isoform X2

    UniProtKB/TrEMBL
    A0A836D898
    Related
    ENSOARP00020000508.2, ENSOART00020000642.2
    Conserved Domains (1) summary
    cd03593
    Location:74 → 197
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

  4. XM_042247549.2 → XP_042103483.1  C-type lectin domain family 7 member A isoform X2

    UniProtKB/TrEMBL
    A0A836D898
    Related
    ENSOARP00020000524.2, ENSOART00020000665.2
    Conserved Domains (1) summary
    cd03593
    Location:74 → 197
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

  5. XM_060413428.1 → XP_060269411.1  C-type lectin domain family 7 member A isoform X3

RNA

  1. XR_006059441.1 RNA Sequence

  2. XR_006059442.1 RNA Sequence

  3. XR_006059440.1 RNA Sequence

  4. XR_006059443.1 RNA Sequence

  5. XR_006059439.2 RNA Sequence

  6. XR_006059438.2 RNA Sequence

  7. XR_009600001.1 RNA Sequence

  8. XR_009600002.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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