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Atg3 autophagy related 3 [ Mus musculus (house mouse) ]

Gene ID: 67841, updated on 28-May-2016
Official Symbol
Atg3provided by MGI
Official Full Name
autophagy related 3provided by MGI
Primary source
MGI:MGI:1915091
See related
Ensembl:ENSMUSG00000022663 Vega:OTTMUSG00000025355
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
APG3; Apg3l; Atg3l; PC3-96; 2610016C12Rik
Orthologs
Location:
16; 16 B5
Exon count:
12
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (45158829..45188538)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (45158942..45188651)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 80 Neighboring gene solute carrier family 35, member A5 Neighboring gene predicted gene, 41456 Neighboring gene predicted gene 6030

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
Atg12 transferase activity IDA
Inferred from Direct Assay
more info
PubMed 
Atg8 ligase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity IEA
Inferred from Electronic Annotation
more info
 
coenzyme F420-0 gamma-glutamyl ligase activity IEA
Inferred from Electronic Annotation
more info
 
coenzyme F420-2 alpha-glutamyl ligase activity IEA
Inferred from Electronic Annotation
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity, elongating IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity, initiating IEA
Inferred from Electronic Annotation
more info
 
ribosomal S6-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
tubulin-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
tubulin-glycine ligase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-like protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
autophagosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
autophagy IEA
Inferred from Electronic Annotation
more info
 
cellular protein modification process ISO
Inferred from Sequence Orthology
more info
 
macroautophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrial fragmentation involved in apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of phagocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
regulation of cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasmic ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
ubiquitin-like-conjugating enzyme ATG3
Names
autophagy-related 3
autophagy-related protein 3
NP_080678.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026402.3NP_080678.1  ubiquitin-like-conjugating enzyme ATG3

    See identical proteins and their annotated locations for NP_080678.1

    Status: PROVISIONAL

    Source sequence(s)
    AC129601
    Consensus CDS
    CCDS28194.1
    UniProtKB/Swiss-Prot
    Q9CPX6
    Related
    ENSMUSP00000023343, OTTMUSP00000030762, ENSMUST00000023343, OTTMUST00000062424
    Conserved Domains (3) summary
    pfam03987
    Location:203265
    Autophagy_act_C; Autophagocytosis associated protein, active-site domain
    pfam03986
    Location:7139
    Autophagy_N; Autophagocytosis associated protein (Atg3), N-terminal domain
    pfam10381
    Location:286310
    Autophagy_Cterm; Autophagocytosis associated protein C-terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    45158829..45188538
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522495.2XP_006522558.1  

    Conserved Domains (3) summary
    pfam03987
    Location:116178
    Autophagy_act_C; Autophagocytosis associated protein, active-site domain
    pfam03986
    Location:152
    Autophagy_N; Autophagocytosis associated protein (Atg3), N-terminal domain
    pfam10381
    Location:199223
    Autophagy_Cterm; Autophagocytosis associated protein C-terminal

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    45552434..45582081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)