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Aadac arylacetamide deacetylase (esterase) [ Mus musculus (house mouse) ]

Gene ID: 67758, updated on 28-May-2016
Official Symbol
Aadacprovided by MGI
Official Full Name
arylacetamide deacetylase (esterase)provided by MGI
Primary source
MGI:MGI:1915008
See related
Ensembl:ENSMUSG00000027761 Vega:OTTMUSG00000022631
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Aada; AI265437; 5033417E09Rik
Orthologs
Location:
3; 3 D
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (60031788..60040157)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (59835710..59844079)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene arylacetamide deacetylase-like 2 pseudogene Neighboring gene arylacetamide deacetylase-like 2 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene succinate receptor 1 Neighboring gene predicted gene, 33650

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
deacetylase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
lipase activity TAS
Traceable Author Statement
more info
PubMed 
serine hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
serine hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
triglyceride lipase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
metabolic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of triglyceride catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
arylacetamide deacetylase
NP_075872.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023383.1NP_075872.1  arylacetamide deacetylase precursor

    See identical proteins and their annotated locations for NP_075872.1

    Status: VALIDATED

    Source sequence(s)
    AF306788
    Consensus CDS
    CCDS17375.1
    UniProtKB/Swiss-Prot
    Q99PG0
    Related
    ENSMUSP00000029325, OTTMUSP00000025846, ENSMUST00000029325, OTTMUST00000054214
    Conserved Domains (2) summary
    COG0657
    Location:26373
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    cl21494
    Location:71198
    Esterase_lipase; Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    60031788..60040157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    59714308..59729435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)