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    FUNDC2 FUN14 domain containing 2 [ Homo sapiens ]

    Gene ID: 65991, updated on 8-Jan-2012
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    Summary

    Official Symbol
    FUNDC2provided by HGNC
    Official Full Name
    FUN14 domain containing 2provided by HGNC
    Primary source
    HGNC:24925
    Locus tag
    GS1-273L24.1
    See related
    Ensembl:ENSG00000165775; HPRD:06586; Vega:OTTHUMG00000013504
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DC44; HCC3; HCBP6; PD03104
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    Genomic context

    Location :
    Xq28
    Sequence :
    Chromosome: X; NC_000023.10 (154255064..154285191)
    See FUNDC2 in Epigenomics, MapViewer

    Chromosome X - NC_000023.10Genomic Context describing neighboring genes Neighboring gene coagulation factor VIII, procoagulant component Neighboring gene zinc finger protein 622 pseudogene Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 31 Neighboring gene mature T-cell proliferation 1 neighbor Neighboring gene mature T-cell proliferation 1 Neighboring gene BRCA1/BRCA2-containing complex, subunit 3

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A directed protein interaction network for investigating intracellular signal transduction. Vinayagam A, et al. Sci Signal, 2011 Sep 6. PMID 21900206.
    2. The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901.
    3. A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.
    4. From ORFeome to biology: a functional genomics pipeline. Wiemann S, et al. Genome Res, 2004 Oct. PMID 15489336.
    5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Brandenberger R, et al. Nat Biotechnol, 2004 Jun. PMID 15146197.

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    FUN14 domain containing 2 ADP ribosylation factor related protein 2 ARL15    HPRD  PubMed  
    FUN14 domain containing 2 Q9H1I8 ASCC2    HPRD  PubMed  
    FUN14 domain containing 2 P56537 EIF6    HPRD  PubMed  
    FUN14 domain containing 2 Q13765 NACA    HPRD  PubMed  
    FUN14 domain containing 2 P46459 NSF    HPRD  PubMed  
    FUN14 domain containing 2 Q08116 RGS1    HPRD  PubMed  
    FUN14 domain containing 2 P21673 SAT1    HPRD  PubMed  
    FUN14 domain containing 2 Q53FA7 TP53I3    HPRD  PubMed  
    FUN14 domain containing 2 Q92995 USP13    HPRD  PubMed  
    BioGRID:122440 BioGRID:120080 ARL15    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:123921 ASCC2    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:109898 EIF6    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:110748 NACA    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:110960 NSF    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:116237 NUDT21    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:111928 RGS1    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:112210 SAT1    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:114915 TP53I3    BioGRID  PubMed Two-hybrid 
    BioGRID:122440 BioGRID:114465 USP13    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Genotypes

    Clone Names

    • MGC2495, FLJ33773, MGC131676

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    FUN14 domain-containing protein 2
    Names
    FUN14 domain-containing protein 2
    HCC-3
    cervical cancer oncogene 3
    cervical cancer proto-oncogene 3 protein
    hepatitis C virus core-binding protein 6
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023934.3 → NP_076423.2  FUN14 domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AF320778, AI886036, BI463291, BM713884, BU738737, CN306694
      Consensus CDS
      CCDS14763.1
      UniProtKB/Swiss-Prot
      Q9BWH2
      Related
      ENSP00000358510, OTTHUMP00000015441, ENST00000369498, OTTHUMT00000037641
      Conserved Domains (1) summary
      cl01015
      Location:86 – 173
      Blast Score: 255
      FUN14; FUN14 family

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000023.10 Reference GRCh37.p5 Primary Assembly

      Range
      154255064..154285191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000155.1 Alternate HuRef

      Range
      142800036..142830182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BX470111.4 CAI41658.1
      CAI41659.1
    genomic CH471172.2 EAW72643.1
      EAW72644.1
    mRNA AF267862.1 AAG44731.1
    mRNA AF320778.1 AAN51931.1
    mRNA AI886036.1 None
    mRNA AJ272054.1 CAC81242.1
    mRNA AK091092.1 None
    mRNA AK313143.1 BAG35962.1
    mRNA AY032594.1 AAK51136.1
    mRNA BC000255.1 AAH00255.2
    mRNA BC072685.1 AAH72685.1
    mRNA BC108657.1 AAI08658.1
    mRNA BI463291.1 None
    mRNA BM713884.1 None
    mRNA BU738737.1 None
    mRNA CN306694.1 None
    other-genetic AM393227.1 CAL38105.1
    other-genetic AM393536.1 CAL38413.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q5HYP8 GenPept UniProtKB/TrEMBL:Q5HYP8
    Q9BWH2.2 GenPept UniProtKB/Swiss-Prot:Q9BWH2
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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