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Htr7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled [ Rattus norvegicus (Norway rat) ]

Gene ID: 65032, updated on 17-May-2016
Official Symbol
Htr7provided by RGD
Official Full Name
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupledprovided by RGD
Primary source
RGD:71034
See related
Ensembl:ENSRNOG00000018827
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
5Ht7
Summary
receptor for 5-hydroxytryptamine; involved in modulatory action on cerebellar function [RGD, Feb 2006]
Orthologs
Location:
1q53
Exon count:
3
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (254547964..254671811, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (261759122..261879914, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene negative elongation factor E-like Neighboring gene similar to initiation factor 2 associated 67 kDa protein Neighboring gene uncharacterized LOC103691348 Neighboring gene ribonuclease P/MRP 30 subunit Neighboring gene ankyrin repeat domain 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
G-protein coupled serotonin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 
neurotransmitter receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
Traceable Author Statement
more info
PubMed 
adenylate cyclase-activating serotonin receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
behavioral response to pain IMP
Inferred from Mutant Phenotype
more info
PubMed 
chemical synaptic transmission, postsynaptic IEA
Inferred from Electronic Annotation
more info
 
circadian rhythm IEA
Inferred from Electronic Annotation
more info
 
detection of mechanical stimulus involved in sensory perception of pain IDA
Inferred from Direct Assay
more info
PubMed 
dopaminergic neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-term synaptic potentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
micturition IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of circadian sleep/wake cycle, REM sleep IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of serotonin secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of neuron projection development IDA
Inferred from Direct Assay
more info
PubMed 
response to corticosterone IDA
Inferred from Direct Assay
more info
PubMed 
response to electrical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
serotonin receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
serotonin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 
synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
urinary bladder smooth muscle contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
vasoconstriction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axon terminus IDA
Inferred from Direct Assay
more info
PubMed 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
postsynapse IEA
Inferred from Electronic Annotation
more info
 
rough endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
5-hydroxytryptamine receptor 7
Names
5-HT-7
5-HT-X
5-HT7
GPRFO
high affinity serotonin receptor (5HT7)
serotonin receptor 7

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022938.2NP_075227.1  5-hydroxytryptamine receptor 7

    See identical proteins and their annotated locations for NP_075227.1

    Status: PROVISIONAL

    Source sequence(s)
    U68489
    UniProtKB/Swiss-Prot
    P32305
    UniProtKB/TrEMBL
    F1LQK9
    Related
    ENSRNOP00000025450, ENSRNOT00000025450
    Conserved Domains (2) summary
    pfam00001
    Location:109387
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:101218
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    254547964..254671811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006231307.2XP_006231369.1  

    See identical proteins and their annotated locations for XP_006231369.1

    UniProtKB/Swiss-Prot
    P32305
    Conserved Domains (2) summary
    pfam00001
    Location:109387
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:101218
    7tm_4; Olfactory receptor

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    230737463..230859847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)