These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_022834.4 → NP_073745.2 von Willebrand factor A domain-containing protein 1 isoform 1 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AL137722, BC059409, BG370349, DB452905
- Consensus CDS
-
CCDS27.1
- UniProtKB/Swiss-Prot
-
Q6PCB0
- Related
- ENSP00000417185, OTTHUMP00000003018, ENST00000476993, OTTHUMT00000008291
- Conserved Domains (3) summary
-
- cd00063
Location:338 – 411
Blast Score: 114
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd01472
Location:34 – 174
Blast Score: 315
- vWA_collagen; von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins. This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form ...
- cl00065
Location:215 – 281
Blast Score: 106
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_199121.2 → NP_954572.2 von Willebrand factor A domain-containing protein 1 isoform 2 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site that causes a frameshift in the central coding region, compared to variant 1. The encoded isoform (2) has a significantly shorter and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AK096773, AL137722, BG370349, DB452905
- Consensus CDS
-
CCDS28.2
- UniProtKB/TrEMBL
-
E9PB53
- UniProtKB/Swiss-Prot
-
Q6PCB0
- Related
- ENSP00000423404, OTTHUMP00000220538, ENST00000338660, OTTHUMT00000008292
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000001.10 Reference GRCh37.p5 Primary Assembly
- Range
- 1370903..1378262
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000133.1 Alternate HuRef
- Range
- 644711..652000
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)