My NCBISign In

Display Settings:

Format

Send to:

Choose Destination

    IQCH IQ motif containing H [ Homo sapiens ]

    Gene ID: 64799, updated on 11-May-2012
    Help top of page

    Summary

    Official Symbol
    IQCHprovided by HGNC
    Official Full Name
    IQ motif containing Hprovided by HGNC
    Primary source
    HGNC:25721
    See related
    Ensembl:ENSG00000103599; HPRD:07773; MIM:612523; Vega:OTTHUMG00000133231
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NYDSP5; FLJ12476; DKFZp434F2114
    Help top of page

    Genomic context

    Location :
    15q23
    Sequence :
    Chromosome: 15; NC_000015.9 (67547138..67794142)
    See IQCH in Epigenomics, MapViewer

    Chromosome 15 - NC_000015.9Genomic Context describing neighboring genes Neighboring gene SMAD family member 3 Neighboring gene alpha- and gamma-adaptin binding protein Neighboring gene ribosomal protein S24 pseudogene 16 Neighboring gene uncharacterized LOC100506686 Neighboring gene chromosome 15 open reading frame 61 Neighboring gene mitogen-activated protein kinase kinase 5 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 5

    Help top of page

    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
    Helptop of page

    Bibliography

    Related articles in PubMed

    1. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Elks CE, et al. Nat Genet, 2010 Dec. PMID 21102462.
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
    3. Genome-wide association analysis with selective genotyping identifies candidate loci for adult height at 8q21.13 and 15q22.33-q23 in Mongolians. Kimura T, et al. Hum Genet, 2008 Jul. PMID 18491143.
    4. Identification of a novel testis-specific gene and its potential roles in testis development/spermatogenesis. Yin LL, et al. Asian J Androl, 2005 Jun. PMID 15897968.
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    2. Genome-wide association study of gene-disease association. (HuGE Navigator)
      Title: Genome-wide association analysis with selective genotyping identifies candidate loci for adult height at 8q21.13 and 15q22.33-q23 in Mongolians.
    Submit: New GeneRIF Correction
    Help top of page

    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

    Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

    Help top of page

    General gene information

    Markers

    Genotypes

    Homology

    Help top of page

    General protein information

    Preferred Names
    IQ domain-containing protein H
    Names
    IQ domain-containing protein H
    testis development protein NYD-SP5
    Help top of page

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031715.2 → NP_001026885.1  IQ domain-containing protein H isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC110292, BC039292, BC039463, BC048964
      Consensus CDS
      CCDS32273.1
      UniProtKB/Swiss-Prot
      Q86VS3
      Related
      ENSP00000336861, OTTHUMP00000164307, ENST00000335894, OTTHUMT00000256969

    2. NM_022784.2 → NP_073621.2  IQ domain-containing protein H isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      BC039463
      Consensus CDS
      CCDS10223.2
      UniProtKB/TrEMBL
      D6RJ88
      Related
      ENSP00000427323, OTTHUMP00000223606, ENST00000512104, OTTHUMT00000372724

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000015.9 Reference GRCh37.p5 Primary Assembly

      Range
      67547138..67794142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000147.1 Alternate HuRef

      Range
      44381488..44628727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Help top of page

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC012568.7 (161651..166784) None
    genomic AC016355.8 (86632..129525) None
    genomic AC106000.6 None
    genomic AC110292.6 None
    genomic CH471082.1 EAW77794.1
      EAW77795.1
      EAW77796.1
      EAW77797.1
    mRNA AK022538.1 BAB14087.1
    mRNA AK292478.1 BAF85167.1
    mRNA AK304303.1 BAG65156.1
    mRNA AL133556.1 CAB63711.1
    mRNA AY014282.2 AAK27307.2
    mRNA BC031041.1 AAH31041.2
    mRNA BC039292.1 AAH39292.1
    mRNA BC039463.1 None
    mRNA BC048964.1 AAH48964.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86VS3.2 GenPept UniProtKB/Swiss-Prot:Q86VS3
    Help top of page

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Medical
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Links

      Links to other resources

      General information

      Related sites

      Feedback

      Subscription

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...