These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_011981.1 RefSeqGene
- Range
- 2835..8248
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001040.3 → NP_001031.2 sex hormone-binding globulin isoform 1 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (1), which has also been referred to as SHBG-L, encodes the longest protein (isoform 1).
- Source sequence(s)
-
AC007421, BC101785, EU352660
- Consensus CDS
-
CCDS11117.1
- UniProtKB/TrEMBL
-
B0FWH2
- UniProtKB/Swiss-Prot
-
P04278
- Related
- ENSP00000369816, OTTHUMP00000135293, ENST00000380450, OTTHUMT00000226957
- Conserved Domains (1) summary
-
- cd00110
Location:67 – 196
Blast Score: 268
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
-
NM_001146279.1 → NP_001139751.1 sex hormone-binding globulin isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter compared to isoform 1.
- Source sequence(s)
-
AC007421, CD013957, EU352660
- UniProtKB/TrEMBL
-
B0FWH2
- Related
- ENSP00000458973, ENST00000575903
- Conserved Domains (1) summary
-
- cd00110
Location:67 – 185
Blast Score: 236
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
-
NM_001146280.1 → NP_001139752.1 sex hormone-binding globulin isoform 3 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate exon in the 3' coding region which results in a frameshift compared to variant 1. Isoform 3 is shorter and has a distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AC007421, CD013955
- Consensus CDS
-
CCDS54082.1
- UniProtKB/TrEMBL
-
F5H5Z8
- Related
- ENSP00000388867, ENST00000416273
- Conserved Domains (1) summary
-
- cd00110
Location:67 – 196
Blast Score: 268
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
-
NM_001146281.1 → NP_001139753.1 sex hormone-binding globulin isoform 4 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks two alternate exons in the 3' coding region but maintains the reading frame compared to variant 1. Isoform 4 is shorter compared to isoform 1.
- Source sequence(s)
-
AC007421, EU352661
- Consensus CDS
-
CCDS54083.1
- UniProtKB/TrEMBL
-
B0FWH4
- UniProtKB/TrEMBL
-
E9PGW1
- Related
- ENSP00000393426, ENST00000441599
- Conserved Domains (1) summary
-
- cd00110
Location:67 – 196
Blast Score: 266
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
RNA
-
NR_027462.1 RNA Sequence
- Description
- Transcript Variant: This variant (5) has an alternate 5' exon and lacks an exon which represents use of an alternate promoter compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC007421, EU352665
-
NR_027463.1 RNA Sequence
- Description
- Transcript Variant: This variant (6) has an alternate 5' exon and lacks an exon which represents use of an alternate promoter compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC007421, EU352670
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000017.10 Reference GRCh37.p5 Primary Assembly
- Range
- 7517382..7536700
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000149.1 Alternate HuRef
- Range
- 7411426..7430707
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)