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    ADORA2A-AS1 ADORA2A antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 646023, updated on 18-Apr-2013
    Official Symbol
    ADORA2A-AS1provided by HGNC
    Official Full Name
    ADORA2A antisense RNA 1provided by HGNC
    Primary source
    HGNC:37122
    See related
    Ensembl:ENSG00000178803
    Gene type
    miscRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C22orf45
    Annotation information
    Note: This locus has been reported as a novel protein-coding gene (Knowled and McLysaght, PMID: 19726446). NCBI has noted that there is uncertainty about the correct definition of the full-length transcript and which of the predicted short open reading frames is translated. Therefore, we have elected to represent the locus as non-coding until additional data supporting a specific protein product becomes available. [18 Sep 2009]
    Location :
    22q11.23
    Sequence :
    Chromosome: 22; NC_000022.10 (24825178..24890783, complement)
    See ADORA2A-AS1 in Epigenomics, MapViewer

    Chromosome 22 - NC_000022.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein S10 pseudogene 29 Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1-like Neighboring gene adenosine A2a receptor Neighboring gene ureidopropionase, beta Neighboring gene guanylyl cyclase domain containing 1

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Recent de novo origin of human protein-coding genes. Knowles DG, et al. Genome Res, 2009 Oct. PMID 19726446.
    2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. C22orf45 is a novel human-specific protein-coding gene.
      Title: Recent de novo origin of human protein-coding genes.
    Submit: New GeneRIF Correction

    Review eQTL and phenotype association data in this region using PheGenI

    Markers

    Genotypes

    Clone Names

    • FLJ34651

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_028483.1 RNA Sequence

      Status: PREDICTED

      Description
      Transcript Variant: This variant (2) is shorter and differs at the 3' end compared to variant 1. The protein coding capacity of this transcript is unknown.
      Source sequence(s)
      BC045098, DB449907
      Related
      ENST00000427813

    2. NR_028484.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. The protein-coding potential of this transcript is unknown.
      Source sequence(s)
      AK091970, BC045098, DA917327, DB449907
      Related
      ENST00000326341

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 104

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p10 Primary Assembly

    Genomic

    1. NC_000022.10 Reference GRCh37.p10 Primary Assembly

      Range
      24825178..24890783, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000154.1 Alternate HuRef

      Range
      7775070..7840450, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.0

    Genomic

    1. NC_018933.1 Alternate CHM1_1.0

      Range
      8748004..8813617, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001039784.1: Suppressed sequence

      Description
      NM_001039784.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    genomic ABBA01055137.1 (5760..56577) None
    genomic ABBA01055138.1 None
    genomic AMYH01012666.1 (5063..70676) None
    genomic AP000355.1 (66297..69509) None
    genomic CH471095.1 EAW59659.1
    mRNA AK091970.1 None
    mRNA BC045098.1 None
    mRNA DA917327.1 None
    mRNA DB449907.2 None
    Protein Accession Links
    GenPept Link UniProtKB Link
    P86434.1 GenPept UniProtKB/Swiss-Prot:P86434

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • BioProjects
        BioProjects related to a gene
      • dbVar
        Link from Gene to dbVar
      • EST
        Link to related EST entry
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • GEO Profiles
        Related GEO
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

      General information

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