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psmb7 proteasome 20S subunit beta 7 [ Danio rerio (zebrafish) ]

Gene ID: 64278, updated on 27-Mar-2024

Summary

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Official Symbol
psmb7provided by ZNC
Official Full Name
proteasome 20S subunit beta 7provided by ZNC
Primary source
ZFIN:ZDB-GENE-001208-4
See related
Ensembl:ENSDARG00000037962 AllianceGenome:ZFIN:ZDB-GENE-001208-4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
beta2; unp311; C167P9.3; zgc:110090
Summary
Predicted to enable kinase activity and threonine-type endopeptidase activity. Predicted to be involved in proteasomal protein catabolic process. Predicted to act upstream of or within phosphorylation and proteolysis involved in cellular protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of proteasome core complex, beta-subunit complex. Predicted to be active in nucleus. Orthologous to human PSMB7 (proteasome 20S subunit beta 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See psmb7 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (8341790..8352095)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (8249251..8259556)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 6, group A, member 1b Neighboring gene nuclear receptor subfamily 5, group A, member 1b Neighboring gene NIMA-related kinase 6 Neighboring gene LIM homeobox 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish GAPDH can be used as a reference gene for expression analysis in cross-subfamily cloned embryos. Pei DS, et al. Anal Biochem, 2007 Apr 15. PMID 17239340
  2. Sequencing of amphioxus PSMB5/8 gene and phylogenetic position of agnathan sequences. Takezaki N, et al. Gene, 2002 Jan 9. PMID 11814690
  3. Analysis of a 26-kb region linked to the Mhc in zebrafish: genomic organization of the proteasome component beta/transporter associated with antigen processing-2 gene cluster and identification of five new proteasome beta subunit genes. Murray BW, et al. J Immunol, 1999 Sep 1. PMID 10453006
  4. Induced Torpor as a Countermeasure for Low Dose Radiation Exposure in a Zebrafish Model. Cahill T, et al. Cells, 2021 Apr 14. PMID 33920039, Free PMC Article
  5. Gene duplication, gene loss and evolution of expression domains in the vertebrate nuclear receptor NR5A (Ftz-F1) family. Kuo MW, et al. Biochem J, 2005 Jul 1. PMID 15725073, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC110090

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of proteasome complex IEA
Inferred from Electronic Annotation
more info
  
part_of proteasome core complex IEA
Inferred from Electronic Annotation
more info
  
part_of proteasome core complex, beta-subunit complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
proteasome subunit beta type-7
Names
proteasome (prosome, macropain) subunit, beta type, 7
proteasome subunit beta 7
NP_001039029.2
XP_021324576.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045564.2 → NP_001039029.2  proteasome subunit beta type-7

    See identical proteins and their annotated locations for NP_001039029.2

    Status: PROVISIONAL

    Source sequence(s)
    AL772368
    UniProtKB/TrEMBL
    A0A8N7XJD0, A4QN82, Q7T002
    Related
    ENSDARP00000112303.2, ENSDART00000129749.4
    Conserved Domains (3) summary
    COG0638
    Location:38 → 236
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03763
    Location:44 → 232
    proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
    pfam12465
    Location:236 → 271
    Pr_beta_C; Proteasome beta subunits C terminal

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    8341790..8352095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468901.1 → XP_021324576.1  proteasome subunit beta type-7 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PQK9
    Related
    ENSDARP00000055324.5, ENSDART00000055325.7
    Conserved Domains (2) summary
    cd03763
    Location:44 → 232
    proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
    pfam12465
    Location:237 → 280
    Pr_beta_C; Proteasome beta subunits C terminal
Nucleotide Protein
Heading Accession and Version

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