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Dhcr7 7-dehydrocholesterol reductase [ Rattus norvegicus (Norway rat) ]

Gene ID: 64191, updated on 26-May-2016
Official Symbol
Dhcr7provided by RGD
Official Full Name
7-dehydrocholesterol reductaseprovided by RGD
Primary source
RGD:621769
See related
Ensembl:ENSRNOG00000020776
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
catalyzes the reduction of 7-dehydrocholesterol and involved in cholesterol biosynthesis [RGD, Feb 2006]
Orthologs
Location:
1q41
Exon count:
10
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (217018916..217034890)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (223874935..223890913)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene MAS related GPR family member E Neighboring gene NAD synthetase 1 Neighboring gene actin-like Neighboring gene SH3 and multiple ankyrin repeat domains 2

Markers

Homology

Clone Names

  • MGC93039

Gene Ontology Provided by RGD

Function Evidence Code Pubs
7-dehydrocholesterol reductase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
7-dehydrocholesterol reductase activity ISO
Inferred from Sequence Orthology
more info
 
7-dehydrocholesterol reductase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
blood vessel development IEA
Inferred from Electronic Annotation
more info
 
blood vessel development ISO
Inferred from Sequence Orthology
more info
 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cholesterol biosynthetic process IC
Inferred by Curator
more info
PubMed 
cholesterol biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
cholesterol biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
cholesterol biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
cholesterol biosynthetic process TAS
Traceable Author Statement
more info
PubMed 
lung development IEA
Inferred from Electronic Annotation
more info
 
lung development ISO
Inferred from Sequence Orthology
more info
 
multicellular organism growth IEA
Inferred from Electronic Annotation
more info
 
multicellular organism growth ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
post-embryonic development IEA
Inferred from Electronic Annotation
more info
 
post-embryonic development ISO
Inferred from Sequence Orthology
more info
 
regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of cholesterol biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
sterol biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
integral component of endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
nuclear outer membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear outer membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
7-dehydrocholesterol reductase
Names
7-DHC reductase
sterol Delta(7)-reductase
NP_071784.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022389.2NP_071784.1  7-dehydrocholesterol reductase

    See identical proteins and their annotated locations for NP_071784.1

    Status: PROVISIONAL

    Source sequence(s)
    AF272393
    UniProtKB/Swiss-Prot
    Q9Z2Z8
    Related
    ENSRNOP00000028194, ENSRNOT00000028195
    Conserved Domains (1) summary
    cl21511
    Location:89471
    PEMT; Phospholipid methyltransferase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    217018916..217034890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230892.2XP_006230954.1  

    See identical proteins and their annotated locations for XP_006230954.1

    UniProtKB/Swiss-Prot
    Q9Z2Z8
    Conserved Domains (1) summary
    cl21511
    Location:89471
    PEMT; Phospholipid methyltransferase
  2. XM_006230894.2XP_006230956.1  

    See identical proteins and their annotated locations for XP_006230956.1

    UniProtKB/Swiss-Prot
    Q9Z2Z8
    Conserved Domains (1) summary
    cl21511
    Location:89471
    PEMT; Phospholipid methyltransferase
  3. XM_006230893.2XP_006230955.1  

    See identical proteins and their annotated locations for XP_006230955.1

    UniProtKB/Swiss-Prot
    Q9Z2Z8
    Related
    ENSRNOP00000071939, ENSRNOT00000078979
    Conserved Domains (1) summary
    cl21511
    Location:89471
    PEMT; Phospholipid methyltransferase
  4. XM_008760171.1XP_008758393.1  

    See identical proteins and their annotated locations for XP_008758393.1

    UniProtKB/Swiss-Prot
    Q9Z2Z8
    Conserved Domains (1) summary
    cl21511
    Location:89471
    PEMT; Phospholipid methyltransferase
  5. XM_008760172.1XP_008758394.1  

    See identical proteins and their annotated locations for XP_008758394.1

    UniProtKB/Swiss-Prot
    Q9Z2Z8
    Conserved Domains (1) summary
    cl21511
    Location:89471
    PEMT; Phospholipid methyltransferase
  6. XM_008760173.1XP_008758395.1  

    See identical proteins and their annotated locations for XP_008758395.1

    UniProtKB/Swiss-Prot
    Q9Z2Z8
    Conserved Domains (1) summary
    cl21511
    Location:89471
    PEMT; Phospholipid methyltransferase
  7. XM_008760170.1XP_008758392.1  

    Conserved Domains (1) summary
    cl21511
    Location:113495
    PEMT; Phospholipid methyltransferase

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    196577886..196593821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)