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    NCAPG non-SMC condensin I complex, subunit G [ Homo sapiens ]

    Gene ID: 64151, updated on 11-May-2012

    Summary

    Official Symbol
    NCAPGprovided by HGNC
    Official Full Name
    non-SMC condensin I complex, subunit Gprovided by HGNC
    Primary source
    HGNC:24304
    See related
    Ensembl:ENSG00000109805; HPRD:12097; MIM:606280; Vega:OTTHUMG00000128539
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CAPG; CHCG; HCAP-G; NY-MEL-3; FLJ12450; MGC126525

    Genomic context

    Location :
    4p15.33
    Sequence :
    Chromosome: 4; NC_000004.11 (17812525..17846488)
    See NCAPG in Epigenomics, MapViewer

    Chromosome 4 - NC_000004.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 184, member B Neighboring gene keratin 18 pseudogene Neighboring gene DDB1 and CUL4 associated factor 16 Neighboring gene ligand dependent nuclear receptor corepressor-like Neighboring gene ribosomal protein L21 pseudogene 46

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    NP_071741.2 NP_004497.1 HSF2    BIND  PubMed HSF2 interacts with CAP-G. 
    Q9BPX3 Q9UBC3 DNMT3B    HPRD  PubMed  
    Q9BPX3 Q03933 HSF2    HPRD  PubMed  
    BioGRID:122089 BioGRID:107420 CDK1    BioGRID  PubMed Biochemical Activity 
    BioGRID:122089 BioGRID:108126 DNMT3B    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:122089 BioGRID:108528 FEN1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:110168 LIG3    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:115246 NCAPD2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:116970 NCAPH    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:122089 BioGRID:110929 NPM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:122089 BioGRID:106652 PARP1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:111419 POLB    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:111420 POLD1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:116327 PTP4A3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:122089 BioGRID:111822 RAD21    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:115841 SMC2    BioGRID  PubMed Affinity Capture-Western; Co-fractionation 
    BioGRID:122089 BioGRID:115362 SMC4    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:122089 BioGRID:113349 XRCC1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:122089 BioGRID:1205541 tat    BioGRID  PubMed Reconstituted Complex 

    General gene information

    Markers

    Homology

    • Homologs of the NCAPG gene: The NCAPG gene is conserved in chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, , S.pombe, , N.crassa, A.thaliana, and rice.
    • Map Viewer (Mouse, Rat)

    Pathways from BioSystems

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    mitosis IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic chromosome condensation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitotic chromosome condensation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    condensin complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    condensin complex subunit 3
    Names
    condensin complex subunit 3
    XCAP-G homolog
    condensin subunit CAP-G
    melanoma antigen NY-MEL-3
    chromosome-associated protein G
    chromosome condensation protein G

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022346.3NP_071741.2  condensin complex subunit 3

      Status: VALIDATED

      Source sequence(s)
      AF331796, AK027511, BG398543, BM743260, BX474610
      Consensus CDS
      CCDS3424.1
      UniProtKB/Swiss-Prot
      Q9BPX3
      Related
      ENSP00000251496, OTTHUMP00000158674, ENST00000251496, OTTHUMT00000250375
      Conserved Domains (3) summary
      COG1413
      Location:143304
      Blast Score: 91
      COG1413; FOG: HEAT repeat [Energy production and conversion]
      pfam12719
      Location:559853
      Blast Score: 614
      Cnd3; Nuclear condensing complex subunits, C-term domain
      pfam13646
      Location:103204
      Blast Score: 94
      HEAT_2; HEAT repeats

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000004.11 Reference GRCh37.p5 Primary Assembly

      Range
      17812525..17846488
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000136.1 Alternate HuRef

      Range
      17167276..17201238
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC005768.17 (42850..76813) None
    genomic CH471069.1 EAW92785.1
    mRNA AB013299.1 BAB21557.1
    mRNA AF235023.1 AAG30732.1
    mRNA AF331796.1 AAG49627.1
    mRNA AK022512.1 BAB14069.1
    mRNA AK023147.1 BAB14429.1
    mRNA AK027511.1 BAB55165.1
    mRNA BC000827.1 AAH00827.1
    mRNA BC002337.2 None
    mRNA BC068467.1 AAH68467.1
    mRNA BC101476.1 AAI01477.1
    mRNA BC143383.1 None
    mRNA BG398543.1 None
    mRNA BM743260.1 None
    mRNA BX474610.1 None
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NUR1 GenPept UniProtKB/TrEMBL:Q6NUR1
    Q9BPX3.1 GenPept UniProtKB/Swiss-Prot:Q9BPX3

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