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    DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 [ Homo sapiens ]

    Gene ID: 63948, updated on 11-May-2012
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    Summary

    Official Symbol
    DMRTB1provided by HGNC
    Official Full Name
    DMRT-like family B with proline-rich C-terminal, 1provided by HGNC
    Primary source
    HGNC:13913
    See related
    Ensembl:ENSG00000143006; HPRD:16828; Vega:OTTHUMG00000008080
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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    Genomic context

    Location :
    1p32.3
    Sequence :
    Chromosome: 1; NC_000001.10 (53925072..53933158)
    See DMRTB1 in Epigenomics, MapViewer

    Chromosome 1 - NC_000001.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100507564 Neighboring gene low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Neighboring gene solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 pseudogene 1 Neighboring gene GLIS family zinc finger 1 Neighboring gene transmembrane protein 48

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Genome-wide association of lipid-lowering response to statins in combined study populations. Barber MJ, et al. PLoS One, 2010 Mar 22. PMID 20339536.
    2. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Lim J, et al. Cell, 2006 May 19. PMID 16713569.
    3. Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

    See all (6) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

    Genome-wide association of lipid-lowering response to statins in combined study populations.

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    DMRTB1 Q01844 EWSR1    HPRD  PubMed  
    DMRTB1 O00167 EYA2    HPRD  PubMed  
    DMRTB1 Q14005 IL16    HPRD  PubMed  
    DMRTB1 Q9NZQ3 NCKIPSD    HPRD  PubMed  
    DMRTB1 Q9GZT8 NIF3L1    HPRD  PubMed  
    DMRTB1 P55345 PRMT2    HPRD  PubMed  
    DMRTB1 Ataxin 2 binding protein 1 RBFOX1    HPRD  PubMed  
    DMRTB1 O43251 RBFOX2    HPRD  PubMed  
    DMRTB1 O60504 SORBS3    HPRD  PubMed  
    DMRTB1 P50552 VASP    HPRD  PubMed  
    BioGRID:122012 BioGRID:108431 EWSR1    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:108440 EYA2    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:109816 IL16    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:119583 NCKIPSD    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:121922 NIF3L1    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:109511 PRMT2    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:117087 RBFOX2    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:115475 SORBS3    BioGRID  PubMed Two-hybrid 
    BioGRID:122012 BioGRID:113251 VASP    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    regulation of transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    sex differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    doublesex- and mab-3-related transcription factor B1
    Names
    doublesex- and mab-3-related transcription factor B1
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033067.1 → NP_149056.1  doublesex- and mab-3-related transcription factor B1

      Status: PROVISIONAL

      Source sequence(s)
      AK057273
      Consensus CDS
      CCDS581.1
      UniProtKB/Swiss-Prot
      Q96MA1
      Related
      ENSP00000360500, OTTHUMP00000009751, ENST00000371445, OTTHUMT00000022110
      Conserved Domains (1) summary
      cl02557
      Location:8 – 53
      Blast Score: 229
      DM; DM DNA binding domain

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000001.10 Reference GRCh37.p5 Primary Assembly

      Range
      53925072..53933158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000133.1 Alternate HuRef

      Range
      52040600..52048686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AL365445.11 CAI22836.1
    genomic CH471059.2 EAX06735.1
      EAX06736.1
    genomic HC006928.1 CBH19269.1
    genomic HC044505.1 CBH30582.1
    mRNA AJ291671.1 CAC40654.1
    mRNA AK057273.1 BAB71407.1
    mRNA AK302085.1 BAG63472.1
    mRNA BC029566.1 AAH29566.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96MA1.1 GenPept UniProtKB/Swiss-Prot:Q96MA1
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
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      Supplemental Content

      Table of contents

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