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RPS25 ribosomal protein S25 [ Homo sapiens (human) ]

Gene ID: 6230, updated on 8-May-2016
Official Symbol
RPS25provided by HGNC
Official Full Name
ribosomal protein S25provided by HGNC
Primary source
HGNC:HGNC:10413
See related
Ensembl:ENSG00000118181 HPRD:01593; MIM:180465
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
S25
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Orthologs
Location:
11q23.3
Exon count:
5
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 11 NC_000011.10 (119015712..119018347, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (118886422..118889057, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene forkhead box R1 Neighboring gene coiled-coil domain containing 84 Neighboring gene ribosomal protein L23a pseudogene 64 Neighboring gene trafficking protein particle complex 4 Neighboring gene microRNA 3656 Neighboring gene solute carrier family 37 member 4

Protein interactions

Protein Gene Interaction Pubs
Rev rev HIV-1 Rev interacting protein, ribosomal protein S25 (RPS25), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding NAS
Non-traceable Author Statement
more info
PubMed 
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
SRP-dependent cotranslational protein targeting to membrane TAS
Traceable Author Statement
more info
 
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
Traceable Author Statement
more info
 
rRNA processing TAS
Traceable Author Statement
more info
 
translation IC
Inferred by Curator
more info
PubMed 
translation NAS
Non-traceable Author Statement
more info
PubMed 
translational initiation TAS
Traceable Author Statement
more info
 
viral transcription TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
cytosol TAS
Traceable Author Statement
more info
 
cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
ribosome IDA
Inferred from Direct Assay
more info
PubMed 
ribosome NAS
Non-traceable Author Statement
more info
PubMed 
small ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001028.2NP_001019.1  40S ribosomal protein S25

    See identical proteins and their annotated locations for NP_001019.1

    Status: REVIEWED

    Source sequence(s)
    BC004986, D28369
    Consensus CDS
    CCDS8406.1
    UniProtKB/Swiss-Prot
    P62851
    Related
    ENSP00000435096, OTTHUMP00000232696, ENST00000527673, OTTHUMT00000389324
    Conserved Domains (1) summary
    pfam03297
    Location:39113
    Ribosomal_S25; S25 ribosomal protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p2 Primary Assembly

    Range
    119015712..119018347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p2 PATCHES

Genomic

  1. NW_009646203.1 Reference GRCh38.p2 PATCHES

    Range
    37312..39947 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 Alternate CHM1_1.1

    Range
    118772705..118775340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)