FKBP14 FKBP prolyl isomerase 14 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: FKBP14provided by VGNC
Official Full Name: FKBP prolyl isomerase 14provided by VGNC
Primary source: VGNC:VGNC:29019
See related: BGD:BT24216; Ensembl:ENSBTAG00000007870
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	4	NC_037331.1 (66328674..66340718)

Chromosome 4 - NC_037331.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables peptidyl-prolyl cis-trans isomerase activity	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: peptidyl-prolyl cis-trans isomerase FKBP14

Names: FK506 binding protein 14, 22 kDa

NP_001069859.2

EC 5.2.1.8

XP_005205563.1

EC 5.2.1.8

XP_059741735.1

EC 5.2.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001076391.4 → NP_001069859.2 peptidyl-prolyl cis-trans isomerase FKBP14 precursor

See identical proteins and their annotated locations for NP_001069859.2

Status: VALIDATED

Source sequence(s)

NKLS02000004

UniProtKB/TrEMBL

F1N4S5

Related

ENSBTAP00000033594.4, ENSBTAT00000033684.5

Conserved Domains (2) summary

COG0545
Location:43 → 135

FkpA; FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones]

pfam13499
Location:141 → 204

EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

Range

66328674..66340718

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005205506.5 → XP_005205563.1 peptidyl-prolyl cis-trans isomerase FKBP14 isoform X1

UniProtKB/TrEMBL

A0A3Q1LWI1

Related

ENSBTAP00000061783.1, ENSBTAT00000068827.2

Conserved Domains (3) summary

pfam00254
Location:38 → 117

FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase

pfam13499
Location:195 → 258

EF-hand_7; EF-hand domain pair

cl08302
Location:196 → 258

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
XM_059885752.1 → XP_059741735.1 peptidyl-prolyl cis-trans isomerase FKBP14 isoform X2

Related

ENSBTAP00000058057.2, ENSBTAT00000082931.2