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DEFB136 defensin, beta 136 [ Homo sapiens (human) ]

Gene ID: 613210, updated on 11-Sep-2014
Official Symbol
DEFB136provided by HGNC
Official Full Name
defensin, beta 136provided by HGNC
Primary source
HGNC:HGNC:34433
See related
Ensembl:ENSG00000205884; Vega:OTTHUMG00000158720
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DEFB137
See DEFB136 in Epigenomics, MapViewer
Location:
8p23.1
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 8 NC_000008.11 (11973937..11974599, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (11831446..11832108, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor, family 7, subfamily E, member 158 pseudogene Neighboring gene olfactory receptor, family 7, subfamily E, member 161 pseudogene Neighboring gene defensin, beta 135 Neighboring gene defensin, beta 134

  • Beta defensins, organism-specific biosystem (from REACTOME)
    Beta defensins, organism-specific biosystemHumans have 38 beta-defensin genes plus 9-10 pseudogenes (details available on the HGNC website at http://www.genenames.org/genefamilies/DEFB). Many beta-defensins are encoded by recently duplicated ...
  • Defensins, organism-specific biosystem (from REACTOME)
    Defensins, organism-specific biosystemThe defensins are a family of antimicrobial cationic peptide molecules which in mammals have a characteristic beta-sheet-rich fold and framework of six disulphide-linked cysteines (Selsted & Ouellet...
  • Immune System, organism-specific biosystem (from REACTOME)
    Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
  • Innate Immune System, organism-specific biosystem (from REACTOME)
    Innate Immune System, organism-specific biosystemInnate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup

Markers

Gene Ontology Provided by GOA

Process Evidence Code Pubs
defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
beta-defensin 136
Names
beta-defensin 136
beta-defensin 137

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033018.2NP_001028190.2  beta-defensin 136 precursor

    See proteins identical to NP_001028190.2

    Status: PROVISIONAL

    Source sequence(s)
    DQ012026
    Consensus CDS
    CCDS43709.1
    UniProtKB/Swiss-Prot
    Q30KP8
    Related
    ENSP00000371644, OTTHUMP00000213327, ENST00000382209, OTTHUMT00000351889

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000008.11 

    Range
    11973937..11974599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000140.1 

    Range
    10762186..10762848
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018919.2 

    Range
    12272852..12273514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)