PABPC1 poly(A) binding protein, cytoplasmic 1 [Canis lupus familiaris (dog)] - Gene

Summary

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Gene symbol: PABPC1
Gene description: poly(A) binding protein, cytoplasmic 1
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis

Genomic context

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Location :: chromosome: 13

Sequence :: Chromosome: 13; NC_006595.3 (2563694..2580550, complement)

See PABPC1 in MapViewer

Chromosome 13 - NC_006595.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Go to reference sequence details

Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from BioSystems

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RNA degradation, organism-specific biosystem (from KEGG)
RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
RNA degradation, conserved biosystem (from KEGG)
RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
RNA transport, organism-specific biosystem (from KEGG)
RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
RNA transport, conserved biosystem (from KEGG)
RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
mRNA surveillance pathway, organism-specific biosystem (from KEGG)
mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
mRNA surveillance pathway, conserved biosystem (from KEGG)
mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...

General gene information

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Markers

GDB:568589 (e-PCR)
- UniSTS:157726

Pabpc1 (e-PCR), detects polymorphism
- UniSTS:265534

SHGC-30876 (e-PCR)
- UniSTS:64326

D13S1095E (e-PCR)
- UniSTS:153224

Pabpc1 (e-PCR), detects polymorphism
- UniSTS:479185

Genotypes

See PABPC1 SNP Geneview Report

Homology

Homologs of the PABPC1 gene: The PABPC1 gene is conserved in human, Rhesus monkey, cow, mouse, rat, chicken, zebrafish, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, and rice.
OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

General protein information

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Preferred Names: polyadenylate-binding protein 1

Names: poly(A) binding protein, cytoplasmic 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Build 3.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

NC_006595.3

Range

2563694..2580550, complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_851615.2 → XP_856708.1

UniProtKB/TrEMBL

J9P326

Conserved Domains (6) summary

TIGR01628
Location:11 – 614
Blast Score: 1959

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

pfam00658
Location:543 – 614
Blast Score: 380

PABP; Poly-adenylate binding protein, unique domain

cd12378
Location:12 – 91
Blast Score: 494

RRM1_I_PABPs; RNA recognition motif 1 in type I polyadenylate-binding proteins

cd12379
Location:97 – 172
Blast Score: 473

RRM2_I_PABPs; RNA recognition motif 2 found in type I polyadenylate-binding proteins

cd12380
Location:190 – 269
Blast Score: 449

RRM3_I_PABPs; RNA recognition motif 3 found in type I polyadenylate-binding proteins

cd12381
Location:293 – 370
Blast Score: 457

RRM4_I_PABPs; RNA recognition motif 4 in type I polyadenylate-binding proteins