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DUSP2 dual specificity phosphatase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 611653, updated on 5-Mar-2024

Summary

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Official Symbol
DUSP2provided by VGNC
Official Full Name
dual specificity phosphatase 2provided by VGNC
Primary source
VGNC:VGNC:40132
See related
Ensembl:ENSCAFG00845006226
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (35357957..35360188)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (34356392..34358603)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (34762735..34764961)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (34487278..34489485)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (34555607..34557809)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 127 Neighboring gene StAR related lipid transfer domain containing 7 Neighboring gene astacin like metalloendopeptidase Neighboring gene adrenoceptor alpha 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoderm formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase 2; LOW QUALITY PROTEIN: dual specificity protein phosphatase 2
XP_038309166.1
XP_038355830.1
XP_038416520.1
XP_038480548.1
XP_038546460.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    35357957..35360188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038690532.1 → XP_038546460.1  dual specificity protein phosphatase 2

    UniProtKB/TrEMBL
    A0A8C0L5C5, A0A8C0NA01, A0A8I3N0J1
    Related
    ENSCAFP00845008622.1, ENSCAFT00845011052.1
    Conserved Domains (2) summary
    cd01446
    Location:8 → 143
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14641
    Location:170 → 313
    DSP_DUSP2; dual specificity phosphatase domain of dual specificity protein phosphatase 2

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    34487278..34489485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038499902.1 → XP_038355830.1  LOW QUALITY PROTEIN: dual specificity protein phosphatase 2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    34555607..34557809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038624620.1 → XP_038480548.1  dual specificity protein phosphatase 2

    Conserved Domains (2) summary
    cd01446
    Location:8 → 143
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14641
    Location:170 → 313
    DSP_DUSP2; dual specificity phosphatase domain of dual specificity protein phosphatase 2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    34762735..34764961
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038560592.1 → XP_038416520.1  LOW QUALITY PROTEIN: dual specificity protein phosphatase 2

    UniProtKB/TrEMBL
    A0A8C0L5C5, A0A8C0NA01, A0A8I3N0J1
    Conserved Domains (2) summary
    cd01446
    Location:8 → 143
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14641
    Location:170 → 313
    DSP_DUSP2; dual specificity phosphatase domain of dual specificity protein phosphatase 2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    34356392..34358603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038453238.1 → XP_038309166.1  dual specificity protein phosphatase 2

    UniProtKB/TrEMBL
    A0A8C0L5C5, A0A8C0NA01, A0A8I3N0J1
    Conserved Domains (2) summary
    cd01446
    Location:8 → 143
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14641
    Location:170 → 313
    DSP_DUSP2; dual specificity phosphatase domain of dual specificity protein phosphatase 2
Nucleotide Protein
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