IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 [Canis lupus familiaris (dog)] - Gene

Summary

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Gene symbol: IMPA2
Gene description: inositol(myo)-1(or 4)-monophosphatase 2
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis

Genomic context

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Location :: chromosome: 7

Sequence :: Chromosome: 7; NC_006589.3 (77620225..77647977)

See IMPA2 in MapViewer

Chromosome 7 - NC_006589.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

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Pathways from BioSystems

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Inositol phosphate metabolism, organism-specific biosystem (from KEGG)
Inositol phosphate metabolism, organism-specific biosystem
Inositol phosphate metabolism
Inositol phosphate metabolism, organism-specific biosystem (from REACTOME)
Inositol phosphate metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Inositol phosphate metabolism, conserved biosystem (from KEGG)
Inositol phosphate metabolism, conserved biosystem
Inositol phosphate metabolism
Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol, organism-specific biosystem (from KEGG)
Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Lipid metabolism
Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol, conserved biosystem (from KEGG)
Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Lipid metabolism
Metabolism, organism-specific biosystem (from REACTOME)
Metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Phosphatidylinositol signaling system, organism-specific biosystem (from KEGG)
Phosphatidylinositol signaling system, organism-specific biosystem
Phosphatidylinositol signaling system
Phosphatidylinositol signaling system, conserved biosystem (from KEGG)
Phosphatidylinositol signaling system, conserved biosystem
Phosphatidylinositol signaling system
Synthesis of IP2, IP, and Ins in the cytosol, organism-specific biosystem (from REACTOME)
Synthesis of IP2, IP, and Ins in the cytosol, organism-specific biosystemcomputationally inferred pathway (not manually curated)

General gene information

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Genotypes

See IMPA2 SNP Geneview Report

Homology

Homologs of the IMPA2 gene: The IMPA2 gene is conserved in human, chimpanzee, Rhesus monkey, cow, mouse, rat, chicken, zebrafish, and fruit fly.
OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

General protein information

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Preferred Names: inositol monophosphatase 2

Names: inositol(myo)-1(or 4)-monophosphatase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Build 3.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

NC_006589.3

Range

77620225..77647977

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_845936.2 → XP_851029.2

Conserved Domains (1) summary

cd01639
Location:23 – 255
Blast Score: 728

IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...