U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 607923, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
HMGCS2provided by VGNC
Official Full Name
3-hydroxy-3-methylglutaryl-CoA synthase 2provided by VGNC
Primary source
VGNC:VGNC:41715
See related
Ensembl:ENSCAFG00845006979
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 17
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (57558992..57577456, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (56315432..56328270, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (57237948..57256436, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (56594625..56613171, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (56620825..56639082, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene phosphoglycerate dehydrogenase Neighboring gene uncharacterized LOC119863968 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC111090692 Neighboring gene regenerating islet-derived protein 4 Neighboring gene disintegrin and metalloproteinase domain-containing protein 30-like Neighboring gene disintegrin and metalloproteinase domain-containing protein 30

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
hydroxymethylglutaryl-CoA synthase, mitochondrial
Names
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
XP_038278791.1
XP_038278793.1
XP_038309253.1
XP_038355287.1
XP_038355288.1
XP_038417854.1
XP_038417855.1
XP_038481926.1
XP_038481927.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    57558992..57577456 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038422865.1 → XP_038278793.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0L843, A0A8C0ML64, A0A8C0SNK3, A0A8I3N1I5
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_038422863.1 → XP_038278791.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0L843, A0A8C0ML64, A0A8C0SNK3, A0A8I3N1I5
    Related
    ENSCAFP00845009713.1, ENSCAFT00845012424.1
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    56594625..56613171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038499360.1 → XP_038355288.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_038499359.1 → XP_038355287.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    56620825..56639082 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038625998.1 → XP_038481926.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_038625999.1 → XP_038481927.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    57237948..57256436 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038561927.1 → XP_038417855.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0L843, A0A8C0ML64, A0A8C0SNK3, A0A8I3N1I5
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_038561926.1 → XP_038417854.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0L843, A0A8C0ML64, A0A8C0SNK3, A0A8I3N1I5
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    56315432..56328270 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038453325.1 → XP_038309253.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8P0SEY0
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 283
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous