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ATG101 autophagy related 101 [ Homo sapiens (human) ]

Gene ID: 60673, updated on 8-May-2016
Official Symbol
ATG101provided by HGNC
Official Full Name
autophagy related 101provided by HGNC
Primary source
HGNC:HGNC:25679
See related
Ensembl:ENSG00000123395 HPRD:08566; MIM:615089; Vega:OTTHUMG00000169611
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C12orf44
Orthologs
Location:
12q13.13
Exon count:
4
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 12 NC_000012.12 (52069974..52077495)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (52463758..52471279)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 4 group A member 1 Neighboring gene uncharacterized LOC105369770 Neighboring gene olfactory receptor family 7 subfamily E member 47 pseudogene Neighboring gene uncharacterized LOC105369771 Neighboring gene keratin 80

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Cellular responses to stress, organism-specific biosystem (from REACTOME)
    Cellular responses to stress, organism-specific biosystemCells are subject to external molecular and physical stresses such as foreign molecules that perturb metabolic or signaling processes, and changes in temperature or pH. The ability of cells and tissu...
  • Longevity regulating pathway, organism-specific biosystem (from KEGG)
    Longevity regulating pathway, organism-specific biosystemRegulation of longevity depends on genetic and environmental factors. Caloric restriction (CR), that is limiting food intake, is recognized in mammals as the best characterized and most reproducible ...
  • Macroautophagy, organism-specific biosystem (from REACTOME)
    Macroautophagy, organism-specific biosystemMacroautophagy (hereafter referred to as autophagy) acts as a buffer against starvation by liberating building materials and energy sources from cellular components. It has additional roles in embryo...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ11773

Gene Ontology Provided by GOA

Function Evidence Code Pubs
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
autophagosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
macroautophagy TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 
pre-autophagosomal structure IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
autophagy-related protein 101
Names
Atg13-interacting protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098673.1NP_001092143.1  autophagy-related protein 101

    See identical proteins and their annotated locations for NP_001092143.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC005151, BP309508, CB137838
    Consensus CDS
    CCDS8820.1
    UniProtKB/Swiss-Prot
    Q9BSB4
    UniProtKB/TrEMBL
    A0A024R128
    Related
    ENSP00000450088, OTTHUMP00000241688, ENST00000553049, OTTHUMT00000405066
    Conserved Domains (1) summary
    pfam07855
    Location:8174
    DUF1649; Protein of unknown function (DUF1649)
  2. NM_021934.4NP_068753.2  autophagy-related protein 101

    See identical proteins and their annotated locations for NP_068753.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC005151, CB137838
    Consensus CDS
    CCDS8820.1
    UniProtKB/Swiss-Prot
    Q9BSB4
    UniProtKB/TrEMBL
    A0A024R128
    Related
    ENSP00000338990, OTTHUMP00000241687, ENST00000336854, OTTHUMT00000405063
    Conserved Domains (1) summary
    pfam07855
    Location:8174
    DUF1649; Protein of unknown function (DUF1649)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p2 Primary Assembly

    Range
    52069974..52077495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    52430002..52437523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)