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MIIP migration and invasion inhibitory protein [ Homo sapiens (human) ]

Gene ID: 60672, updated on 11-Sep-2014
Official Symbol
MIIPprovided by HGNC
Official Full Name
migration and invasion inhibitory proteinprovided by HGNC
Primary source
HGNC:HGNC:25715
Locus tag
RP5-1077B9.4
See related
Ensembl:ENSG00000116691; HPRD:07768; MIM:608772; Vega:OTTHUMG00000002439
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IIP45
Summary
This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers. [provided by RefSeq, Sep 2011]
See MIIP in Epigenomics, MapViewer
Location:
1p36.22
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 1 NC_000001.11 (12019242..12032049)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (12079299..12092106)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 Neighboring gene mitofusin 2 Neighboring gene microRNA 6729 Neighboring gene tumor necrosis factor receptor superfamily, member 8 Neighboring gene tumor necrosis factor receptor superfamily, member 1B Neighboring gene microRNA 7846

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ12438, FLJ38609
Preferred Names
migration and invasion-inhibitory protein
Names
migration and invasion-inhibitory protein
IGFBP2-binding protein
invasion-inhibitory protein 45

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_030022.1 

    Range
    5001..17808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_021933.3NP_068752.2  migration and invasion-inhibitory protein

    See proteins identical to NP_068752.2

    Status: REVIEWED

    Source sequence(s)
    FJ618905
    Consensus CDS
    CCDS143.1
    UniProtKB/Swiss-Prot
    Q5JXC2
    Related
    ENSP00000235332, OTTHUMP00000002537, ENST00000235332, OTTHUMT00000006941

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000001.11 

    Range
    12019242..12032049
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005263487.1XP_005263544.1  

Alternate HuRef

Genomic

  1. AC_000133.1 

    Range
    11233976..11246748
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 

    Range
    12067052..12079859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001025374.1: Suppressed sequence

    Description
    NM_001025374.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.