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    Cenpk centromere protein K [ Mus musculus (house mouse) ]

    Gene ID: 60411, updated on 26-Feb-2013
    Official Symbol
    Cenpkprovided by MGI
    Official Full Name
    centromere protein Kprovided by MGI
    Primary source
    MGI:1926210
    See related
    Ensembl:ENSMUSG00000021714
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Solt; Solzt; Cenp-K; BB232189; B130045K24Rik; C530004N04Rik
    Location :
    13 D1; 13
    Sequence :
    Chromosome: 13; NC_000079.6 (104228955..104249617)
    See Cenpk in Epigenomics, MapViewer

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 23 Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 Neighboring gene predicted gene 8680 Neighboring gene CWC27 spliceosome-associated protein homolog (S. cerevisiae)

    Related articles in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    centromere protein K
    Names
    centromere protein K
    SoxLZ/Sox6 leucine zipper binding protein in testis

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021790.2NP_068562.1  centromere protein K isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses alternate 5' exon structure, differs in the 5' UTR, and includes an alternate 3' terminal exon compared to variant 2. This transcript also initiates translation at an alternate start codon, resulting in isoform 1, which is longer and has distinct N- and C-termini compared to isoform 2.
      Source sequence(s)
      AB043687, AC154216, AV367397
      Consensus CDS
      CCDS26749.1
      UniProtKB/Swiss-Prot
      Q9ESN5
      Related
      ENSMUSP00000022227, ENSMUST00000022227
      Conserved Domains (1) summary
      pfam11802
      Location:36306
      Blast Score: 1050
      CENP-K; Centromere-associated protein K
    2. NM_181061.5NP_851406.1  centromere protein K isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longest transcript and encodes the shorter isoform (2).
      Source sequence(s)
      AK082939, BC028655
      Consensus CDS
      CCDS26750.1
      UniProtKB/Swiss-Prot
      Q9ESN5
      Related
      ENSMUSP00000070910, ENSMUST00000070761
      Conserved Domains (1) summary
      pfam11802
      Location:1228
      Blast Score: 781
      CENP-K; Centromere-associated protein K

    RNA

    1. NR_075088.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site in an internal exon and includes an alternate 3' terminal exon, compared to variant 2. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC154216, AV367397, BC028655

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p1 C57BL/6J

      Range
      104228955..104249617
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000035.1 Alternate Mm_Celera

      Range
      108621358..108642051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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