We are sorry, but NCBI web applications do not support your browser, and may not function properly. More information here...

RASA1 RAS p21 protein activator (GTPase activating protein) 1 [ Homo sapiens ]

Gene ID: 5921, updated on 5-Feb-2012

Help top of page

Summary

Official Symbol: RASA1provided by HGNC
Official Full Name: RAS p21 protein activator (GTPase activating protein) 1provided by HGNC
Primary source: HGNC:9871
See related: Ensembl:ENSG00000145715; HPRD:00745; MIM:139150; Vega:OTTHUMG00000162605
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: GAP; PKWS; RASA; CMAVM; CM-AVM; RASGAP; p120GAP; p120RASGAP
Summary: The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues. [provided by RefSeq, Jul 2008]

Help top of page

Genomic context

Location :: 5q13.3

Sequence :: Chromosome: 5; NC_000005.9 (86564151..86687733)

See RASA1 in Epigenomics, MapViewer

Chromosome 5 - NC_000005.9 Genomic Context describing neighboring genes

Help top of page

Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Help top of page

Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Cell adhesion to the substrate is necessary for RasGAP to bind Nck1. Cell detachment makes RasGAP incapable of associating with Nck1 and decreases RasGAP activity.
Title: Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates its activity.
The results assign an unexpected role for p120RasGAP in the regulation of integrin traffic in cancer cells and reveal a new concept of competitive binding of Rab GTPases and GAP proteins to receptors as a regulatory mechanism in trafficking.
Title: Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration.
Nck1 activates RasGAP by direct binding in the substrate-attached but not in the suspended cells.
Title: Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates its activity.
An important role is revealed for p120 RasGAP (RASA1) as a transgenic regulator of CD4+CD8+ double-positive cell survival and positive selection in the thymus as well as naive T cell survival in the periphery.
Title: A role for p120 RasGAP in thymocyte positive selection and survival of naive T cells.
Ras mutation cooperates with beta-catenin activation to drive bladder tumourigenesis.
Title: Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.
Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities
Title: Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.
A novel synonymous mutation (c.1229 G > A [p.K420K]) of RASA1 was identified in a Chinese population with sporadic Sturge-Weber syndrome
Title: Detection of RASA1 mutations in patients with sporadic Sturge-Weber syndrome.
Sema4D/Plexin-B1 promotes the dephosphorylation and activation of PTEN through the R-Ras GAP activity, inducing growth cone collapse.
Title: Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons.
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas.
miR-132 acts as an angiogenic switch by suppressing endothelial p120RasGAP expression.
Title: MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis.

Submit: New GeneRIF Correction See all (33)

Help top of page

Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

Capillary malformation-arteriovenous malformation

MIM: 608354

Meta-analysis of genome-wide association studies for personality.

Products	Interactant	Other Gene	Source	Pubs	Description
NP_002881.1	NP_009297.1	ABL1	BIND	PubMed	c-Abl interacts with GAP.
NP_002881.1	NP_001146.1	ANXA6	BIND	PubMed	Annexin VI interacts with GAP.
NP_002881.1	NP_001164.1	ARHGAP5	BIND	PubMed	GAP interacts with p190. This interaction was modeled on a demonstrated interaction between human GAP and rat p190.
NP_002881.1	NP_003591.2	AURKA	BIND	PubMed	RasGAP interacts with HsAIRK-1.
NP_002881.1	NP_004208.1	AURKB	BIND	PubMed	RasGAP interacts with HsAIRK-2 in the RasGAP/HsAIRK-2/survivin complex.
NP_002881.1	NP_004318.2	BCR	BIND	PubMed	BCR interacts with GAP. This interaction was modeled on a demonstrated interaction between BCR from an unspecified source and human GAP.
NP_002881.1	NP_001372.1	DOK1	BIND	PubMed	DOK1 interacts with RASGAP
NP_002881.1	NP_003965.2	DOK2	BIND	PubMed	Dok2 interacts with RASGAP
NP_002881.1	NP_005219.2	EGFR	BIND	PubMed	GAP interacts with EGFR.
NP_002881.1	NP_006089.1	GNB2L1	BIND	PubMed	RACK1 interacts with p120GAP.This interaction was modeled on a demonstrated interaction between RACK1 from mouse and rat, and human p120GAP.
NP_002881.1	NP_002102.2	HTT	BIND	PubMed	HDP interacts with RasGAP.
NP_002881.1	NP_006550.1	KHDRBS1	BIND	PubMed	Sam68 interacts with the SH2 domains of p120GAP, preferentially with the C-terminal SH2 domain. This interaction was modelled based on a demonstrated interaction between rat proteins.
NP_002881.1	NP_002600.1	PDGFRB	BIND	PubMed	N-terminal SH2 domain of GAP interacts with PDGFR. This interaction was modeled on a demonstrated interaction between GAP from human and PDGFR from an unspecified species.
NP_002881.1	NP_002600.1	PDGFRB	BIND	PubMed	Activated PDGFR interacts with GAP. This interaction was modeled on a demonstrated interaction between human PDGFR and canine GAP.
NP_002881.1	NP_002600.1	PDGFRB	BIND	PubMed	Autophosphorylated PDGFR interacts with GAP. This interaction was modelled on a demonstrated interaction between human PDGFR and GAP from an unspecified species.
NP_002881.1	NP_056888.1	src	BIND	PubMed	Rous sarcoma virus v-Src phosphorylates human GAP.
P20936	P00519	ABL1	HPRD	PubMed
P20936	Q8N4X5	AFAP1L2	HPRD	PubMed
P20936	P08133	ANXA6	HPRD	PubMed
P20936	Q07960	ARHGAP1	HPRD	PubMed
P20936	Q13017	ARHGAP5	HPRD	PubMed
P20936	Q96GD4	AURKB	HPRD	PubMed
P20936	P11274	BCR	HPRD	PubMed
P20936	O15392	BIRC5	HPRD	PubMed
P20936	P42574	CASP3	HPRD	PubMed
P20936	P55210	CASP7	HPRD	PubMed
P20936	P51636	CAV2	HPRD	PubMed
P20936	P06127	CD5	HPRD	PubMed
P20936	P07333	CSF1R	HPRD	PubMed
P20936	P41240	CSK	HPRD	PubMed
P20936	Q96EY1	DNAJA3	HPRD	PubMed
P20936	Q99704	DOK1	HPRD	PubMed
P20936	O60496	DOK2	HPRD	PubMed
P20936	Q8TEW6	DOK4	HPRD	PubMed
P20936	P00533	EGFR	HPRD	PubMed
P20936	P29317	EPHA2	HPRD	PubMed
P20936	P29323	EPHB2	HPRD	PubMed
P20936	P54753	EPHB3	HPRD	PubMed
P20936	P07332	FES	HPRD	PubMed
P20936	Q13283	G3BP1	HPRD	PubMed
P20936	P63244	GNB2L1	HPRD	PubMed
P20936	P62993	GRB2	HPRD	PubMed
P20936	P08631	HCK	HPRD	PubMed
P20936	P01112	HRAS	HPRD	PubMed
P20936	P10809	HSPD1	HPRD	PubMed
P20936	P42858	HTT	HPRD	PubMed
P20936	P08069	IGF1R	HPRD	PubMed
P20936	P06213	INSR	HPRD	PubMed
P20936	P35968	KDR	HPRD	PubMed
P20936	Q07666	KHDRBS1	HPRD	PubMed
P20936	P10721	KIT	HPRD	PubMed
P20936	P06239	LCK	HPRD	PubMed
P20936	P07948	LYN	HPRD	PubMed
P20936	Q96QZ7	MAGI1	HPRD	PubMed
P20936	O95819	MAP4K4	HPRD	PubMed
P20936	P16333	NCK1	HPRD	PubMed
P20936	P04629	NTRK1	HPRD	PubMed
P20936	Q9NWQ8	PAG1	HPRD	PubMed
P20936	O43924	PDE6D	HPRD	PubMed
P20936	P09619	PDGFRB	HPRD	PubMed
P20936	P27986	PIK3R1	HPRD	PubMed
P20936	Q14289	PTK2B	HPRD	PubMed
P20936	P08575	PTPRC	HPRD	PubMed
P20936	P49023	PXN	HPRD	PubMed
P20936	P20339	RAB5A	HPRD	PubMed
P20936	P62834	RAP1A	HPRD	PubMed
P20936	P20936	RASA1	HPRD	PubMed
P20936	P29353	SHC1	HPRD	PubMed
P20936	Q9UBY0	SLC9A2	HPRD	PubMed
P20936	O14543	SOCS3	HPRD	PubMed
P20936	Q96BD6	SPSB1	HPRD	PubMed
P20936	P12931	SRC	HPRD	PubMed
P20936	O95793	STAU1	HPRD	PubMed
P20936	P43405	SYK	HPRD	PubMed
P20936	P17600	SYN1	HPRD	PubMed
P20936	Q9H0M0	WWP1	HPRD	PubMed
P20936	O00308	WWP2	HPRD	PubMed
P20936	P07947	YES1	HPRD	PubMed
P20936	P43403	ZAP70	HPRD	PubMed
BioGRID:111856	BioGRID:106806	ANXA6	BioGRID	PubMed	Far Western; Reconstituted Complex
BioGRID:111856	BioGRID:109166	ARHGAP35	BioGRID	PubMed	Reconstituted Complex
BioGRID:111856	BioGRID:122851	BBS10	BioGRID	PubMed	Two-hybrid
BioGRID:111856	BioGRID:114457	BTRC	BioGRID	PubMed	Phenotypic Suppression
BioGRID:111856	BioGRID:107306	CAV2	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:107359	CD5	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:107832	CSK	BioGRID	PubMed	Reconstituted Complex
BioGRID:111856	BioGRID:114547	DNAJA3	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:108131	DOK1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:114508	DOK2	BioGRID	PubMed	Affinity Capture-Western
	NP_060580.2	DOK4	BIND	PubMed	IRS5/DOK4 interacts with RasGAP. This interaction was modelled on a demonstrated interaction between human IRS5/DOK4 and hamster RasGAP.
BioGRID:111856	BioGRID:108276	EGFR	BioGRID	PubMed	Reconstituted Complex
BioGRID:111856	BioGRID:115504	EIF1	BioGRID	PubMed	Two-hybrid
BioGRID:111856	BioGRID:108362	EPHB2	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:108363	EPHB3	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:108446	EZH2	BioGRID	PubMed	Two-hybrid
BioGRID:111856	BioGRID:115448	G3BP1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:115671	GNB2L1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:109142	GRB2	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:109305	HCK	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:109501	HRAS	BioGRID	PubMed	Biochemical Activity; Co-crystal Structure; Reconstituted Complex
BioGRID:111856	BioGRID:109314	HTT	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:109701	IGF1R	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:109854	INSR	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:109992	KDR	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:115900	KHDRBS1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:110124	LCK	BioGRID	PubMed	Biochemical Activity
BioGRID:111856	BioGRID:114838	MAP4K4	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:110770	NCK1	BioGRID	PubMed	Affinity Capture-Western; Far Western; Reconstituted Complex
BioGRID:111856	BioGRID:110859	NFKBIA	BioGRID	PubMed	Phenotypic Suppression
BioGRID:111856	BioGRID:111185	PDGFRB	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:111351	PLCG1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:108480	PTK2B	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:111787	PXN	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:111285	SERPINA4	BioGRID	PubMed	Two-hybrid
BioGRID:111856	BioGRID:112439	SLC9A2	BioGRID	PubMed	Reconstituted Complex
BioGRID:111856	BioGRID:114488	SOCS3	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111856	BioGRID:112592	SRC	BioGRID	PubMed	Affinity Capture-Western; Biochemical Activity
BioGRID:111856	BioGRID:112719	SYN1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:117968	TRMT2A	BioGRID	PubMed	Two-hybrid
BioGRID:111856	BioGRID:108822	XRCC6	BioGRID	PubMed	Two-hybrid
BioGRID:111856	BioGRID:113357	YES1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:113367	ZAP70	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111856	BioGRID:127842	ZNF579	BioGRID	PubMed	Two-hybrid

Function	Evidence Code	Pubs
GTPase binding	IPI Inferred from Physical Interaction more info	PubMed
Ras GTPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
glycoprotein binding	IPI Inferred from Physical Interaction more info	PubMed
potassium channel inhibitor activity	NAS Non-traceable Author Statement more info	PubMed
protein binding	IPI Inferred from Physical Interaction more info
receptor binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
cytokinesis	ISS Inferred from Sequence or Structural Similarity more info
embryo development	ISS Inferred from Sequence or Structural Similarity more info
intracellular signal transduction	NAS Non-traceable Author Statement more info	PubMed
negative regulation of Ras protein signal transduction	IBA Inferred from Biological aspect of Ancestor more info
negative regulation of cell adhesion	IDA Inferred from Direct Assay more info	PubMed
negative regulation of cell-matrix adhesion	IDA Inferred from Direct Assay more info	PubMed
negative regulation of neuron apoptosis	ISS Inferred from Sequence or Structural Similarity more info
positive regulation of Ras GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
positive regulation of Ras GTPase activity	TAS Traceable Author Statement more info	PubMed
positive regulation of anti-apoptosis	IDA Inferred from Direct Assay more info	PubMed
regulation of RNA metabolic process	NAS Non-traceable Author Statement more info	PubMed
regulation of actin filament polymerization	IDA Inferred from Direct Assay more info	PubMed
regulation of cell shape	NAS Non-traceable Author Statement more info	PubMed
regulation of small GTPase mediated signal transduction	IEA Inferred from Electronic Annotation more info
signal transduction	IDA Inferred from Direct Assay more info	PubMed
vasculogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
cytoplasm	NAS Non-traceable Author Statement more info	PubMed
cytosol	TAS Traceable Author Statement more info
intrinsic to internal side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
plasma membrane	IEA Inferred from Electronic Annotation more info
ruffle	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: ras GTPase-activating protein 1

Names: ras GTPase-activating protein 1; triphosphatase-activating protein

Help top of page

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_011650.1 RefSeqGene

Range

4920..128593

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_002890.2 → NP_002881.1 ras GTPase-activating protein 1 isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (1) lacks the alternatively spliced insert found in variant 2, resulting in translation of the longer isoform (1).

Source sequence(s)

AB209106, CF528258, M23379

Consensus CDS

CCDS34200.1

UniProtKB/Swiss-Prot

P20936

UniProtKB/TrEMBL

Q59GK3

Related

ENSP00000274376, OTTHUMP00000222390, ENST00000274376, OTTHUMT00000369729

Conserved Domains (6) summary

cd00174
Location:295 – 338
Blast Score: 101

SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...

cd05391
Location:721 – 1035
Blast Score: 1498

RasGAP_p120GAP; p120GAP is a negative regulator of Ras that stimulates hydrolysis of bound GTP to GDP. Once the Ras regulator p120GAP, a member of the GAP protein family, is recruited to the membrane, it is transiently immobilized to interact with Ras-GTP. The down ...

cd08400
Location:591 – 716
Blast Score: 620

C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)

cd01245
Location:494 – 575
Blast Score: 260

PH_RasGAP_CG5898; RAS GTPase-activating protein (GAP) CG5898 Pleckstrin homology (PH) domain

cd10353
Location:161 – 264
Blast Score: 562

SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)

cd10354
Location:350 – 426
Blast Score: 412

SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
NM_022650.2 → NP_072179.1 ras GTPase-activating protein 1 isoform 2

Status: REVIEWED

Description

Transcript Variant: This variant (2) includes an alternatively spliced exon in the 5' portion of the transcript, allowing for translation from an alternative initiation codon and resulting in the shorter isoform (2) which is missing the hydrophobic amino terminus found in isoform 1.

Source sequence(s)

CF528258, DA863496, M23612

Consensus CDS

CCDS47243.1

UniProtKB/Swiss-Prot

P20936

Related

ENSP00000411221, OTTHUMP00000222391, ENST00000456692, OTTHUMT00000369730

Conserved Domains (6) summary

cd00174
Location:118 – 161
Blast Score: 101

SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...

cd05391
Location:544 – 858
Blast Score: 1499

RasGAP_p120GAP; p120GAP is a negative regulator of Ras that stimulates hydrolysis of bound GTP to GDP. Once the Ras regulator p120GAP, a member of the GAP protein family, is recruited to the membrane, it is transiently immobilized to interact with Ras-GTP. The down ...

cd08400
Location:414 – 539
Blast Score: 620

C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)

cd01245
Location:317 – 398
Blast Score: 258

PH_RasGAP_CG5898; RAS GTPase-activating protein (GAP) CG5898 Pleckstrin homology (PH) domain

cd10354
Location:173 – 249
Blast Score: 408

SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)

cl15255
Location:4 – 87
Blast Score: 462

SH2; Src homology 2 (SH2) domain

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000005.9 Reference GRCh37.p5 Primary Assembly

Range

86564151..86687733

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000137.1 Alternate HuRef

Range

81768484..81891898

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Help top of page

Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC010410.8	None
genomic	AC018754.6 (117133..139996)	None
genomic	AC035142.4 (2902..84684)	None
genomic	AC126776.2 (15654..34334)	None
genomic	CH471084.1	EAW95931.1
		EAW95932.1
		EAW95933.1
mRNA	AB209106.1	BAD92343.1
mRNA	AK300263.1	BAG62024.1
mRNA	AK300269.1	BAG62030.1
mRNA	AK300406.1	BAG62136.1
mRNA	AK312739.1	BAG35610.1
mRNA	BC020761.1	AAH20761.1
mRNA	BC033015.2	AAH33015.1
mRNA	BC054891.1	AAH54891.1
mRNA	BC070063.1	None
mRNA	BC107870.1	None
mRNA	CF528258.1	None
mRNA	CR749722.1	CAH18488.2
mRNA	DA863496.1	None
mRNA	M23379.1	AAA52517.1
mRNA	M23612.1	AAA35865.1

Protein Accession	Links
Protein Accession	GenePept Link	UniProtKB Link
P20936.1	GenPept	UniProtKB/Swiss-Prot:P20936
Q05CU5	GenPept	UniProtKB/TrEMBL:Q05CU5
Q59GK3	GenPept	UniProtKB/TrEMBL:Q59GK3
Q68CU6	GenPept	UniProtKB/TrEMBL:Q68CU6
Q7Z4M2	GenPept	UniProtKB/TrEMBL:Q7Z4M2

Help top of page

Additional Links

Epigenomics
MIM 139150
RASA1base: Database for pathogenic mutations in the RasGAP SH2 domain RASA1base/
PharmGKB PA34232
GeneTests for MIM: 139150
UCSC UCSC
UniGene Hs.664080