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Foxm1 forkhead box M1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 58921, updated on 26-May-2016
Official Symbol
Foxm1provided by RGD
Official Full Name
forkhead box M1provided by RGD
Primary source
RGD:61807
See related
Ensembl:ENSRNOG00000005936
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
putative transcription factor; may play a role in the control of cell proliferation [RGD, Feb 2006]
Orthologs
Location:
4q42
Exon count:
9
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (161685283..161697633)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (226891344..226903694)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene tubby-like protein 3 Neighboring gene RAD9-HUS1-RAD1 interacting nuclear orphan 1 Neighboring gene rCG30099-like Neighboring gene nuclear receptor-interacting protein 2-like Neighboring gene nuclear receptor interacting protein 2 Neighboring gene integrin alpha FG-GAP repeat containing 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
protein kinase binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor activity, sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor activity, sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription factor activity, sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IEA
Inferred from Electronic Annotation
more info
 
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator ISO
Inferred from Sequence Orthology
more info
 
DNA repair IEA
Inferred from Electronic Annotation
more info
 
G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
G2/M transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
G2/M transition of mitotic cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
 
liver development ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell aging IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell aging ISO
Inferred from Sequence Orthology
more info
 
negative regulation of stress-activated MAPK cascade IEA
Inferred from Electronic Annotation
more info
 
negative regulation of stress-activated MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of double-strand break repair IEA
Inferred from Electronic Annotation
more info
 
positive regulation of double-strand break repair ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
regulation of Ras protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
regulation of cell cycle arrest IEA
Inferred from Electronic Annotation
more info
 
regulation of cell cycle arrest ISO
Inferred from Sequence Orthology
more info
 
regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of reactive oxygen species metabolic process IEA
Inferred from Electronic Annotation
more info
 
regulation of reactive oxygen species metabolic process ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to cAMP IEP
Inferred from Expression Pattern
more info
PubMed 
response to gonadotropin IEP
Inferred from Expression Pattern
more info
PubMed 
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
vasculogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
forkhead box protein M1
Names
INS-1 winged helix
winged-helix factor from INS-1 cells

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031633.3NP_113821.2  forkhead box protein M1

    Status: VALIDATED

    Source sequence(s)
    AC103290
    UniProtKB/TrEMBL
    D3ZLE1
    Related
    ENSRNOP00000008003, ENSRNOT00000008003
    Conserved Domains (1) summary
    cd00059
    Location:235322
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

    Range
    161685283..161697633
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006237418.2XP_006237480.1  

    Conserved Domains (1) summary
    cd00059
    Location:236311
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  2. XM_006237421.2XP_006237483.1  

    See identical proteins and their annotated locations for XP_006237483.1

    Conserved Domains (1) summary
    cd00059
    Location:236311
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  3. XM_006237420.2XP_006237482.1  

    Conserved Domains (1) summary
    cd00059
    Location:236311
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  4. XM_006237416.2XP_006237478.1  

    Conserved Domains (1) summary
    cd00059
    Location:237312
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  5. XM_006237417.2XP_006237479.1  

    UniProtKB/TrEMBL
    F1LN13
    Related
    ENSRNOP00000008012, ENSRNOT00000008012
    Conserved Domains (1) summary
    cd00059
    Location:237312
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  6. XM_006237419.2XP_006237481.1  

    Conserved Domains (1) summary
    cd00059
    Location:237312
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

Alternate Rn_Celera

Genomic

  1. AC_000072.1 Alternate Rn_Celera

    Range
    150341256..150352278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)