These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001199867.1 → NP_001186796.1 MAP/microtubule affinity-regulating kinase 4 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AB049127, AB058763, AY120867, DB100014
- Consensus CDS
-
CCDS56097.1
- UniProtKB/Swiss-Prot
-
Q96L34
- Related
- ENSP00000262891, ENST00000262891
- Conserved Domains (4) summary
-
- cd00194
Location:331 – 368
Blast Score: 101
- UBA; Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been ...
- pfam02149
Location:707 – 752
Blast Score: 157
- KA1; Kinase associated domain 1
- smart00220
Location:59 – 310
Blast Score: 875
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl09925
Location:58 – 306
Blast Score: 668
- PKc_like; Protein Kinases, catalytic domain
-
NM_031417.3 → NP_113605.2 MAP/microtubule affinity-regulating kinase 4 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) includes an alternate exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AB049127, AB058763, DB100014
- Consensus CDS
-
CCDS12658.1
- UniProtKB/Swiss-Prot
-
Q96L34
- Related
- ENSP00000300843, ENST00000300843
- Conserved Domains (3) summary
-
- cd00194
Location:331 – 368
Blast Score: 101
- UBA; Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been ...
- cd05123
Location:65 – 298
Blast Score: 666
- STKc_AGC; Catalytic domain of AGC family Protein Serine/Threonine Kinases
- smart00220
Location:59 – 310
Blast Score: 877
- S_TKc; Serine/Threonine protein kinases, catalytic domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000019.9 Reference GRCh37.p5 Primary Assembly
- Range
- 45754516..45808541
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000151.1 Alternate HuRef
- Range
- 42186730..42240375
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)