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    Sec61a2 Sec61, alpha subunit 2 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 57743, updated on 4-May-2013
    Official Symbol
    Sec61a2provided by MGI
    Official Full Name
    Sec61, alpha subunit 2 (S. cerevisiae)provided by MGI
    Primary source
    MGI:1931071
    Locus tag
    RP23-307E15.4
    See related
    Ensembl:ENSMUSG00000025816; Vega:OTTMUSG00000010876
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Location :
    2 A1; 2
    Sequence :
    Chromosome: 2; NC_000068.7 (5870987..5895353, complement)
    See Sec61a2 in Epigenomics, MapViewer

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene cell division cycle 123 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 5 Neighboring gene predicted gene 13199 Neighboring gene dehydrogenase E1 and transketolase domain containing 1 Neighboring gene UPF2 regulator of nonsense transcripts homolog (yeast)

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068.
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693.
    4. Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress. Hori O, et al. Mol Cell Biol, 2006 Jun. PMID 16705175.
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073.

    See all (15) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ribosome binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
    		  
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Preferred Names
    protein transport protein Sec61 subunit alpha isoform 2
    Names
    protein transport protein Sec61 subunit alpha isoform 2
    Sec61 alpha
    sec61 alpha-2
    protein transport protein Sec61 subunit alpha

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021305.3 → NP_067280.1  protein transport protein Sec61 subunit alpha isoform 2

      Status: PROVISIONAL

      Source sequence(s)
      AL928924
      Consensus CDS
      CCDS15668.1
      UniProtKB/Swiss-Prot
      Q9JLR1
      Related
      ENSMUSP00000100046, OTTMUSP00000011664, ENSMUST00000102981, OTTMUST00000025464
      Conserved Domains (3) summary
      PTZ00219
      Location:1 – 469
      Blast Score: 2149
      PTZ00219; Sec61 alpha subunit; Provisional
      pfam10559
      Location:40 – 74
      Blast Score: 158
      Plug_translocon; Plug domain of Sec61p
      pfam00344
      Location:75 – 459
      Blast Score: 676
      SecY; SecY translocase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p1 C57BL/6J

      Range
      5870987..5895353, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000024.1 Alternate Mm_Celera

      Range
      5822085..5848609, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01013627.1 None
    genomic AAHY01013628.1 None
    genomic AAHY01013629.1 None
    genomic AAHY01013630.1 None
    genomic AL928924.12 (84932..109299) None
    genomic CH466542.1 EDL07972.1 mixed
      EDL07973.1 mixed
    mRNA AF145254.1 AAF66696.1
    mRNA AF222748.1 AAG44253.1
    mRNA AK017615.1 BAB30840.1 C57BL/6J
    mRNA AK077701.1 BAC36967.1 C57BL/6J
    mRNA AK136447.1 None C57BL/6J
    mRNA AK160602.1 None C57BL/6J
    mRNA AK161316.1 BAE36319.1 C57BL/6J
    mRNA BC005458.1 AAH05458.1 CZECHII
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JLR1.3 GenPept UniProtKB/Swiss-Prot:Q9JLR1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

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