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    ODF2L outer dense fiber of sperm tails 2-like [ Homo sapiens ]

    Gene ID: 57489, updated on 11-May-2012
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    Summary

    Official Symbol
    ODF2Lprovided by HGNC
    Official Full Name
    outer dense fiber of sperm tails 2-likeprovided by HGNC
    Primary source
    HGNC:29225
    See related
    Ensembl:ENSG00000122417; HPRD:11134; Vega:OTTHUMG00000010080
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    dJ977L11.1; RP5-977L11.1; KIAA1229; MGC111060
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    Genomic context

    Location :
    1p22.3
    Sequence :
    Chromosome: 1; NC_000001.10 (86812507..86862025, complement)
    See ODF2L in Epigenomics, MapViewer

    Chromosome 1 - NC_000001.10Genomic Context describing neighboring genes Neighboring gene zinc finger, HIT-type containing 6 Neighboring gene collagen, type XXIV, alpha 1 Neighboring gene ribosomal protein L7-like 1 pseudogene Neighboring gene chloride channel accessory 2

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Danielsen JM, et al. Mol Cell Proteomics, 2011 Mar. PMID 21139048.
    2. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins JR, et al. Science, 2010 Apr 30. PMID 20360068.
    3. A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
    5. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Nagase T, et al. DNA Res, 1999 Oct 29. PMID 10574462.

    See all (6) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    Outer dense fiber of sperm tails 2-like P21860 ERBB3    HPRD  PubMed  
    Outer dense fiber of sperm tails 2-like Q9P2H0 KIAA1377    HPRD  PubMed  
    Outer dense fiber of sperm tails 2-like Q9P0Z9 PIPOX    HPRD  PubMed  
    Outer dense fiber of sperm tails 2-like O95084 PRSS23    HPRD  PubMed  
    BioGRID:121557 BioGRID:108377 ERBB3    BioGRID  PubMed Two-hybrid 
    BioGRID:121557 BioGRID:121617 KIAA1377    BioGRID  PubMed Two-hybrid 
    BioGRID:121557 BioGRID:211904 Ndc80    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:121557 BioGRID:116279 PRSS23    BioGRID  PubMed Two-hybrid 
    BioGRID:121557 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    centrosome IDA
    Inferred from Direct Assay
    more info
    		  
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    General protein information

    Preferred Names
    outer dense fiber protein 2-like
    Names
    outer dense fiber protein 2-like
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007022.2 → NP_001007023.2  outer dense fiber protein 2-like isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1, resulting in a protein (isoform b) that maintains the reading frame but is longer than isoform a.
      Source sequence(s)
      AB033055, AK303209, AL136382, BC047368, BX499763, CD687053
      Consensus CDS
      CCDS41354.2
      UniProtKB/Swiss-Prot
      Q9ULJ1
      Related
      ENSP00000359600, OTTHUMP00000011769, ENST00000359242, OTTHUMT00000027873
      Conserved Domains (1) summary
      COG1196
      Location:80 – 338
      Blast Score: 89
      Smc; Chromosome segregation ATPases [Cell division and chromosome partitioning]

    2. NM_001184765.1 → NP_001171694.1  outer dense fiber protein 2-like isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform c) has a distinct C-terminus but is the same length as isoform a.
      Source sequence(s)
      AK303209, AL136382, BC047368, BC091490, BM993592, BX499763, CD687053
      UniProtKB/Swiss-Prot
      Q9ULJ1
      Related
      ENSP00000320165, ENST00000317336

    3. NM_001184766.1 → NP_001171695.1  outer dense fiber protein 2-like isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform d) has a distinct C-terminus and is shorter than isoform a.
      Source sequence(s)
      AK303209, AL136382, BC047368, BM993592, BX499763, CD687053
      Consensus CDS
      CCDS53339.1
      UniProtKB/Swiss-Prot
      Q9ULJ1
      Related
      ENSP00000359597, ENST00000370566

    4. NM_020729.2 → NP_065780.2  outer dense fiber protein 2-like isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform a.
      Source sequence(s)
      AK303209, AL136382, BC047368, BX499763, CD687053
      Consensus CDS
      CCDS30763.2
      UniProtKB/Swiss-Prot
      Q9ULJ1
      Related
      ENSP00000294678, OTTHUMP00000011770, ENST00000294678, OTTHUMT00000027874
      Conserved Domains (1) summary
      COG1196
      Location:80 – 338
      Blast Score: 87
      Smc; Chromosome segregation ATPases [Cell division and chromosome partitioning]

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000001.10 Reference GRCh37.p5 Primary Assembly

      Range
      86812507..86862025, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000133.1 Alternate HuRef

      Range
      84923290..84973009, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC119749.2 None
    genomic AL136382.6 CAI23513.1
      CAI23514.1
    genomic CH471097.2 EAW73188.1
      EAW73189.1
      EAW73190.1
      EAW73191.1
      EAW73192.1
    mRNA AB033055.1 BAA86543.1
    mRNA AK302792.1 BAG63995.1
    mRNA AK303209.1 BAG64299.1
    mRNA AK308351.1 None
    mRNA BC009779.1 AAH09779.1
    mRNA BC012579.1 None
    mRNA BC026105.2 None
    mRNA BC029420.1 AAH29420.1
    mRNA BC047368.1 AAH47368.1
    mRNA BC091490.1 AAH91490.1
    mRNA BG777878.1 None
    mRNA BI768058.1 None
    mRNA BM971230.1 None
    mRNA BM993592.1 None
    mRNA BQ894001.1 None
    mRNA BX499763.1 None
    mRNA CD687053.1 None
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96GC1 GenPept UniProtKB/TrEMBL:Q96GC1
    Q9ULJ1.2 GenPept UniProtKB/Swiss-Prot:Q9ULJ1
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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