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Ppbp pro-platelet basic protein [ Mus musculus (house mouse) ]

Gene ID: 57349, updated on 8-May-2016
Official Symbol
Ppbpprovided by MGI
Official Full Name
pro-platelet basic proteinprovided by MGI
Primary source
MGI:MGI:1888712
See related
Ensembl:ENSMUSG00000029372 Vega:OTTMUSG00000055504
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TGB; LDGF; MDGF; TGB1; CTAP3; Cxcl7; NAP-2; Scyb7; b-TG1; LA-PF4; THBGB1; CTAPIII; beta-TG; AI854500; NAP-2-L1; 2400003M24Rik
Orthologs
Location:
5; 5 E1
Exon count:
3
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (90768518..90770060)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (91197544..91199086)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36084 Neighboring gene chemokine (C-X-C motif) ligand 5 Neighboring gene platelet factor 4 Neighboring gene chemokine (C-X-C motif) ligand 3

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
CXCR chemokine receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
chemokine activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
chemokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
leukocyte migration involved in inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of leukocyte chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
response to lipopolysaccharide IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
platelet basic protein
Names
chemokine (C-X-C motif) ligand 7

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023785.3NP_076274.1  platelet basic protein precursor

    See identical proteins and their annotated locations for NP_076274.1

    Status: VALIDATED

    Source sequence(s)
    AK010273, BQ030657
    Consensus CDS
    CCDS19415.1
    UniProtKB/TrEMBL
    Q9EQI5
    Related
    ENSMUSP00000031319, OTTMUSP00000072359, ENSMUST00000031319, OTTMUST00000137379
    Conserved Domains (1) summary
    cd00273
    Location:49111
    Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

    Range
    90768518..90770060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p3 129S1/SvImJ

Genomic

  1. NT_109599.1 Reference GRCm38.p3 129S1/SvImJ

    Range
    56669..58211 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 Alternate Mm_Celera

    Range
    88920145..88921687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)