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KCMF1 potassium channel modulatory factor 1 [ Homo sapiens (human) ]

Gene ID: 56888, updated on 12-May-2016
Official Symbol
KCMF1provided by HGNC
Official Full Name
potassium channel modulatory factor 1provided by HGNC
Primary source
HGNC:HGNC:20589
See related
Ensembl:ENSG00000176407 HPRD:13761; MIM:614719; Vega:OTTHUMG00000153004
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FIGC; PCMF; ZZZ1; DEBT91
Orthologs
Location:
2p11.2
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 2 NC_000002.12 (84971108..85059472)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (85198231..85286595)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374838 Neighboring gene ribosomal protein S2 pseudogene 17 Neighboring gene uncharacterized LOC100996478 Neighboring gene LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 3

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp434L1021

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ligase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
E3 ubiquitin-protein ligase KCMF1
Names
FGF-induced in gastric cancer
FGF-induced ubiquitin-protein ligase in gastric cancers
ZZ-type zinc finger-containing protein 1
differentially expressed in branching tubulogenesis 91
zinc finger, ZZ domain containing 1
NP_064507.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020122.4NP_064507.3  E3 ubiquitin-protein ligase KCMF1

    See identical proteins and their annotated locations for NP_064507.3

    Status: VALIDATED

    Source sequence(s)
    AC078974, AK023403, AW466865, CT004343
    Consensus CDS
    CCDS46350.1
    UniProtKB/Swiss-Prot
    Q9P0J7
    Related
    ENSP00000386738, OTTHUMP00000202861, ENST00000409785, OTTHUMT00000328942
    Conserved Domains (3) summary
    cd02338
    Location:755
    ZZ_PCMF_like; Zinc finger, ZZ type. Zinc finger present in potassium channel modulatory factor (PCMF) 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Human potassium channel ...
    pfam05605
    Location:76137
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    pfam14571
    Location:280328
    Di19_C; Stress-induced protein Di19, C-terminal

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p2 Primary Assembly

    Range
    84971108..85059472
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006712052.2XP_006712115.1  

    Conserved Domains (3) summary
    cd02338
    Location:1563
    ZZ_PCMF_like; Zinc finger, ZZ type. Zinc finger present in potassium channel modulatory factor (PCMF) 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Human potassium channel ...
    pfam05605
    Location:84145
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    pfam14571
    Location:288336
    Di19_C; Stress-induced protein Di19, C-terminal
  2. XM_011532990.1XP_011531292.1  

    See identical proteins and their annotated locations for XP_011531292.1

    Conserved Domains (2) summary
    pfam05605
    Location:2586
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    pfam14571
    Location:229277
    Di19_C; Stress-induced protein Di19, C-terminal

Alternate CHM1_1.1

Genomic

  1. NC_018913.2 Alternate CHM1_1.1

    Range
    85128041..85216367
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)