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gramd1ba GRAM domain containing 1Ba [ Danio rerio (zebrafish) ]

Gene ID: 568698, updated on 27-Mar-2024

Summary

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Official Symbol
gramd1baprovided by ZNC
Official Full Name
GRAM domain containing 1Baprovided by ZNC
Primary source
ZFIN:ZDB-GENE-091118-87
See related
Ensembl:ENSDARG00000075383 AllianceGenome:ZFIN:ZDB-GENE-091118-87
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-249g19.1
Summary
Predicted to act upstream of or within lipid transport. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Predicted to be integral component of membrane. Orthologous to human GRAMD1B (GRAM domain containing 1B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 10
Exon count:
27
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (40160496..40275205)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (40239026..40354084)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene small fragment nuclease Neighboring gene CXADR like membrane protein Neighboring gene G protein-coupled receptor kinase interacting ArfGAP 2b Neighboring gene glycolipid transfer protein b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Thyme SB, et al. Cell, 2019 Apr 4. PMID 30929901, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cholesterol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cholesterol transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular sterol transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum-plasma membrane contact site IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GRAM domain-containing protein 1B-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    40160496..40275205
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479453.1 → XP_021335128.1  GRAM domain-containing protein 1B-like isoform X2

    UniProtKB/TrEMBL
    A0A8M9Q6Q6
    Related
    ENSDARP00000141724.2, ENSDART00000171879.3
    Conserved Domains (2) summary
    cd13220
    Location:253 → 346
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:521 → 669
    DUF4782; Domain of unknown function (DUF4782)

  2. XM_009305617.3 → XP_009303892.1  GRAM domain-containing protein 1B-like isoform X3

    UniProtKB/TrEMBL
    A0A8M3AX65
    Related
    ENSDARP00000146441.1, ENSDART00000188277.1
    Conserved Domains (2) summary
    cd13220
    Location:124 → 217
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:401 → 545
    DUF4782; Domain of unknown function (DUF4782)

  3. XM_009305618.3 → XP_009303893.1  GRAM domain-containing protein 1B-like isoform X4

    UniProtKB/TrEMBL
    A0A8M3BDB3
    Related
    ENSDARP00000114542.2, ENSDART00000145862.3
    Conserved Domains (2) summary
    cd13220
    Location:120 → 213
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:397 → 541
    DUF4782; Domain of unknown function (DUF4782)

  4. XM_009305619.3 → XP_009303894.1  GRAM domain-containing protein 1B-like isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q098
    Conserved Domains (2) summary
    cd13220
    Location:63 → 156
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:340 → 488
    DUF4782; Domain of unknown function (DUF4782)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394797.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    2079..41300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472372.1 → XP_021328047.1  GRAM domain-containing protein 1B-like isoform X5

    UniProtKB/TrEMBL
    A0A8M9PAI9
    Conserved Domains (2) summary
    cd13220
    Location:84 → 177
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:361 → 509
    DUF4782; Domain of unknown function (DUF4782)

  2. XM_021472373.1 → XP_021328048.1  GRAM domain-containing protein 1B-like isoform X6

    UniProtKB/TrEMBL
    A0A8M9PLY7
    Conserved Domains (2) summary
    cd13220
    Location:69 → 162
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:337 → 485
    DUF4782; Domain of unknown function (DUF4782)

  3. XM_021472374.1 → XP_021328049.1  GRAM domain-containing protein 1B-like isoform X7

    UniProtKB/TrEMBL
    A0A8M9PT23
    Conserved Domains (2) summary
    cd13220
    Location:69 → 162
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:337 → 485
    DUF4782; Domain of unknown function (DUF4782)

  4. XM_021472371.1 → XP_021328046.1  GRAM domain-containing protein 1B-like isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q098
    Conserved Domains (2) summary
    cd13220
    Location:63 → 156
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:340 → 488
    DUF4782; Domain of unknown function (DUF4782)
Nucleotide Protein Strain
Heading Accession and Version

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