Format

Send to:

Choose Destination

Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 [ Mus musculus (house mouse) ]

Gene ID: 56847, updated on 29-May-2016
Official Symbol
Aldh1a3provided by MGI
Official Full Name
aldehyde dehydrogenase family 1, subfamily A3provided by MGI
Primary source
MGI:MGI:1861722
See related
Ensembl:ENSMUSG00000015134 Vega:OTTMUSG00000036917
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
V1; ALDH6; RALDH3
Orthologs
Location:
7; 7 C
Exon count:
13
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 7 NC_000073.6 (66390892..66427477, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (73535778..73572363, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33442 Neighboring gene leucine-rich repeat kinase 1 Neighboring gene microRNA 7057 Neighboring gene predicted gene, 33515 Neighboring gene predicted gene, 33570

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
3-chloroallyl aldehyde dehydrogenase activity TAS
Traceable Author Statement
more info
PubMed 
NAD+ binding IDA
Inferred from Direct Assay
more info
PubMed 
aldehyde dehydrogenase (NAD) activity IDA
Inferred from Direct Assay
more info
PubMed 
aldehyde dehydrogenase [NAD(P)+] activity IDA
Inferred from Direct Assay
more info
PubMed 
aldehyde dehydrogenase [NAD(P)+] activity ISO
Inferred from Sequence Orthology
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
retinal dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
thyroid hormone binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular aldehyde metabolic process IEA
Inferred from Electronic Annotation
more info
 
embryonic camera-type eye development IGI
Inferred from Genetic Interaction
more info
PubMed 
embryonic eye morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
embryonic eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
face development IGI
Inferred from Genetic Interaction
more info
PubMed 
inner ear morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
neuromuscular process controlling balance IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleus accumbens development IMP
Inferred from Mutant Phenotype
more info
PubMed 
olfactory pit development IMP
Inferred from Mutant Phenotype
more info
PubMed 
optic cup morphogenesis involved in camera-type eye development IGI
Inferred from Genetic Interaction
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of retinoic acid receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
PubMed 
retinal metabolic process ISO
Inferred from Sequence Orthology
more info
 
retinoic acid biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
retinoic acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
retinoic acid metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
retinoic acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
retinoic acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
righting reflex IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
aldehyde dehydrogenase family 1 member A3
Names
RALDH-3
aldehyde dehydrogenase 6
aldehyde dehydrogenase-6
retinaldehyde dehydrogenase 3
NP_444310.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053080.3NP_444310.3  aldehyde dehydrogenase family 1 member A3

    See identical proteins and their annotated locations for NP_444310.3

    Status: VALIDATED

    Source sequence(s)
    AK147006, BC038646
    Consensus CDS
    CCDS21345.1
    UniProtKB/Swiss-Prot
    Q9JHW9
    UniProtKB/TrEMBL
    Q3UIA4
    Related
    ENSMUSP00000015278, OTTMUSP00000052868, ENSMUST00000015278, OTTMUST00000094854
    Conserved Domains (2) summary
    cd07141
    Location:26506
    ALDH_F1AB_F2_RALDH1; NAD+-dependent retinal dehydrogenase 1, ALDH families 1A, 1B, and 2-like
    PLN02466
    Location:19512
    PLN02466; aldehyde dehydrogenase family 2 member

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p3 C57BL/6J

    Range
    66390892..66427477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000029.1 Alternate Mm_Celera

    Range
    63845586..63882073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)