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c5 complement component 5 [ Danio rerio (zebrafish) ]

Gene ID: 565774, updated on 18-Jul-2015
Official Symbol
c5provided by ZNC
Official Full Name
complement component 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-120510-2
See related
Ensembl:ENSDARG00000021004
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Orthologs
See c5 in MapViewer
Location:
chromosome: 5
Exon count:
42
Annotation release Status Assembly Chr Location
104 current GRCz10 (GCF_000002035.5) 5 NC_007116.6 (62764789..62816237, complement)
103 previous assembly Zv9 (GCF_000002035.4) 5 NC_007116.5 (66661434..66712897)

Chromosome 5 - NC_007116.6Genomic Context describing neighboring genes Neighboring gene RAB14, member RAS oncogene family Neighboring gene centriolin Neighboring gene PR domain containing 12b Neighboring gene surfeit gene 4, like

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IEA
Inferred from Electronic Annotation
more info
 

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz10 Primary Assembly

Genomic

  1. NC_007116.6 Reference GRCz10 Primary Assembly

    Range
    62764789..62816237
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001919191.6XP_001919226.4  

    Related
    ENSDARP00000088095, ENSDART00000097325
    Conserved Domains (9) summary
    cd00017
    Location:687756
    ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
    pfam00207
    Location:786873
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:124218
    A2M_N; MG2 domain
    pfam07677
    Location:14381528
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:10631322
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:468616
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
    pfam11974
    Location:17103
    MG1; Alpha-2-macroglobulin MG1 domain
    cl02512
    Location:15461698
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
    cl08267
    Location:10051320
    ISOPREN_C2_like; This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate ...