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Ick intestinal cell kinase [ Mus musculus (house mouse) ]

Gene ID: 56542, updated on 8-May-2016
Official Symbol
Ickprovided by MGI
Official Full Name
intestinal cell kinaseprovided by MGI
Primary source
MGI:MGI:1934157
See related
Ensembl:ENSMUSG00000009828 Vega:OTTMUSG00000031751
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mrk; AI848300; 2210420N10Rik
Orthologs
Location:
9; 9 E1
Exon count:
16
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (78109192..78172114)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (77956999..78019917)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene f-box protein 9 Neighboring gene RIKEN cDNA C920006O11 gene Neighboring gene RNA, 7SK, nuclear

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding ISO
Inferred from Sequence Orthology
more info
 
cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell projection organization IEA
Inferred from Electronic Annotation
more info
 
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
cilium assembly ISO
Inferred from Sequence Orthology
more info
 
intracellular signal transduction ISO
Inferred from Sequence Orthology
more info
 
intraciliary transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
signal transduction TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cell projection IEA
Inferred from Electronic Annotation
more info
 
ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
ciliary tip IMP
Inferred from Mutant Phenotype
more info
PubMed 
ciliary tip ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
serine/threonine-protein kinase ICK
Names
MAK-related kinase
mICK
NP_001157252.1
NP_064371.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163780.1NP_001157252.1  serine/threonine-protein kinase ICK

    See identical proteins and their annotated locations for NP_001157252.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC159313
    Consensus CDS
    CCDS40697.1
    UniProtKB/Swiss-Prot
    Q9JKV2
    Related
    ENSMUSP00000112961, OTTMUSP00000041856, ENSMUST00000118869, OTTMUST00000078653
    Conserved Domains (2) summary
    smart00220
    Location:4284
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07830
    Location:4284
    STKc_MAK_like; Catalytic domain of Male germ cell-Associated Kinase-like Serine/Threonine Kinases
  2. NM_019987.2NP_064371.2  serine/threonine-protein kinase ICK

    See identical proteins and their annotated locations for NP_064371.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC159313, AK087484, AK173068, BM935223
    Consensus CDS
    CCDS40697.1
    UniProtKB/Swiss-Prot
    Q9JKV2
    UniProtKB/TrEMBL
    Q69ZV0
    Related
    ENSMUSP00000048234, OTTMUSP00000041854, ENSMUST00000044551, OTTMUST00000078650
    Conserved Domains (2) summary
    smart00220
    Location:4284
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07830
    Location:4284
    STKc_MAK_like; Catalytic domain of Male germ cell-Associated Kinase-like Serine/Threonine Kinases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    78109192..78172114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511304.2XP_006511367.1  

    See identical proteins and their annotated locations for XP_006511367.1

    UniProtKB/Swiss-Prot
    Q9JKV2
    Conserved Domains (2) summary
    smart00220
    Location:4284
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07830
    Location:4284
    STKc_MAK_like; Catalytic domain of Male germ cell-Associated Kinase-like Serine/Threonine Kinases
  2. XM_006511305.2XP_006511368.1  

    Conserved Domains (2) summary
    smart00220
    Location:4203
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07830
    Location:1203
    STKc_MAK_like; Catalytic domain of Male germ cell-Associated Kinase-like Serine/Threonine Kinases

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    75286395..75349194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)