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PARD3 par-3 family cell polarity regulator [ Homo sapiens (human) ]

Gene ID: 56288, updated on 19-Jul-2014
Official Symbol
PARD3provided by HGNC
Official Full Name
par-3 family cell polarity regulatorprovided by HGNC
Primary source
HGNC:16051
Locus tag
RP11-406D17.1
See related
Ensembl:ENSG00000148498; HPRD:05994; MIM:606745; Vega:OTTHUMG00000017948
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Baz; ASIP; PAR3; PARD-3; PARD3A; SE2-5T2; PPP1R118; SE2-5L16; SE2-5LT1; PAR3alpha
Summary
This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
See PARD3 in Epigenomics, MapViewer
Location:
10p11.21
Exon count:
31
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 10 NC_000010.11 (34109560..34815325, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (34398488..35104253, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 838 Neighboring gene ribosomal protein L23 pseudogene 11 Neighboring gene transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) pseudogene 4 Neighboring gene ribosomal protein L37 pseudogene 18 Neighboring gene ribosomal protein S12 pseudogene 16 Neighboring gene PARD3 antisense RNA 1 Neighboring gene synovial sarcoma translocation gene on chromosome 18-like 2 pseudogene 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population.
NHGRI GWA Catalog
Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples.
NHGRI GWA Catalog
Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.
NHGRI GWA Catalog
Germline genomic variants associated with childhood acute lymphoblastic leukemia.
NHGRI GWA Catalog
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  • Neuroactive ligand-receptor interaction, organism-specific biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, organism-specific biosystem
    Neuroactive ligand-receptor interaction
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Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ21015

Gene Ontology Provided by GOA

Function Evidence Code Pubs
phosphatidylinositol-3,4,5-trisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
phosphatidylinositol-3-phosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
phosphatidylinositol-4,5-bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase C binding IEA
Inferred from Electronic Annotation
more info
 
protein phosphatase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
apical constriction IEA
Inferred from Electronic Annotation
more info
 
asymmetric cell division TAS
Traceable Author Statement
more info
PubMed 
axonogenesis TAS
Traceable Author Statement
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell junction assembly TAS
Traceable Author Statement
more info
 
cell-cell junction organization TAS
Traceable Author Statement
more info
 
centrosome localization IEA
Inferred from Electronic Annotation
more info
 
establishment of epithelial cell polarity ISS
Inferred from Sequence or Structural Similarity
more info
 
establishment or maintenance of cell polarity TAS
Traceable Author Statement
more info
PubMed 
microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
myelination in peripheral nervous system ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of peptidyl-threonine phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of myelination ISS
Inferred from Sequence or Structural Similarity
more info
 
protein complex assembly TAS
Traceable Author Statement
more info
PubMed 
protein kinase C-activating G-protein coupled receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
protein targeting to membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of actin filament-based process IEA
Inferred from Electronic Annotation
more info
 
regulation of cellular localization IEA
Inferred from Electronic Annotation
more info
 
tight junction assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
tight junction assembly TAS
Traceable Author Statement
more info
 
transforming growth factor beta receptor signaling pathway TAS
Traceable Author Statement
more info
 
wound healing, spreading of cells IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
apical part of cell IEA
Inferred from Electronic Annotation
more info
 
axonal growth cone IEA
Inferred from Electronic Annotation
more info
 
cell cortex IEA
Inferred from Electronic Annotation
more info
 
cell junction IDA
Inferred from Direct Assay
more info
 
cell junction TAS
Traceable Author Statement
more info
 
cell-cell adherens junction IEA
Inferred from Electronic Annotation
more info
 
cell-cell junction IDA
Inferred from Direct Assay
more info
 
cell-cell junction ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol TAS
Traceable Author Statement
more info
 
endomembrane system IEA
Inferred from Electronic Annotation
more info
 
internode region of axon ISS
Inferred from Sequence or Structural Similarity
more info
 
neuronal cell body IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 
protein complex IEA
Inferred from Electronic Annotation
more info
 
spindle IEA
Inferred from Electronic Annotation
more info
 
tight junction IDA
Inferred from Direct Assay
more info
PubMed 
tight junction ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
partitioning defective 3 homolog
Names
partitioning defective 3 homolog
bazooka
PAR3-alpha
CTCL tumor antigen se2-5
par-3 partitioning defective 3 homolog
par-3 family cell polarity regulator alpha
protein phosphatase 1, regulatory subunit 118
atypical PKC isotype-specific interacting protein
atypical PKC isotype-specific-interacting protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001184785.1NP_001171714.1  partitioning defective 3 homolog isoform 2

    See proteins identical to NP_001171714.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1. This variant has also been called the 'long variant' and 'variant b'.
    Source sequence(s)
    AF196185, AK024668, AL160409, AL450337, AW242451
    Consensus CDS
    CCDS53515.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000363920, OTTHUMP00000019429, ENST00000374788, OTTHUMT00000047528
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  2. NM_001184786.1NP_001171715.1  partitioning defective 3 homolog isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate, in-frame segment and uses a different splice site, in the coding region, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AK025892, AL160409, AL450337, AW242451, BC071566
    Consensus CDS
    CCDS53511.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000443147, ENST00000545693
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  3. NM_001184787.1NP_001171716.1  partitioning defective 3 homolog isoform 4

    See proteins identical to NP_001171716.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate, in-frame segment in the coding region, compared to variant 1. The resulting protein (isoform 4) is shorter when it is compared to isoform 1. This variant has also been called 'variant d'.
    Source sequence(s)
    AF332592, AF467004, AL160409, AL450337, AW242451
    Consensus CDS
    CCDS53514.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000340591, OTTHUMP00000019430, ENST00000346874, OTTHUMT00000047529
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 642
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  4. NM_001184788.1NP_001171717.1  partitioning defective 3 homolog isoform 5

    See proteins identical to NP_001171717.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an alternate, in-frame segment and uses two different splice sites, in the coding region, compared to variant 1. The resulting protein (isoform 5) is shorter when it is compared to isoform 1. This variant has also been called 'variant f'.
    Source sequence(s)
    AF332592, AF467006, AL160409, AL450337, AW242451
    Consensus CDS
    CCDS53512.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000311986, OTTHUMP00000019432, ENST00000350537, OTTHUMT00000047531
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 198
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  5. NM_001184789.1NP_001171718.1  partitioning defective 3 homolog isoform 6

    See proteins identical to NP_001171718.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two alternate, in-frame segments and uses two different splice sites, in the coding region, compared to variant 1. The resulting protein (isoform 6) is shorter when it is compared to isoform 1. This variant has also been called 'long variant b'.
    Source sequence(s)
    AF332593, AF467006, AK024668, AL160409, AL450337, AW242451
    UniProtKB/Swiss-Prot
    Q8TEW0
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 643
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  6. NM_001184790.1NP_001171719.1  partitioning defective 3 homolog isoform 7

    See proteins identical to NP_001171719.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks two alternate, in-frame segments and uses two different splice sites, in the coding region, compared to variant 1. The resulting protein (isoform 7) is shorter when it is compared to isoform 1. This variant has also been called 'variant c'.
    Source sequence(s)
    AB073671, AF252293, AF467003, AL160409, AL450337, AW242451
    Consensus CDS
    CCDS53510.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000440857, ENST00000545260
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 643
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:421500
    Blast Score: 197
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  7. NM_001184791.1NP_001171720.1  partitioning defective 3 homolog isoform 8

    See proteins identical to NP_001171720.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) lacks four alternate, in-frame segments and uses a different splice site, in the coding region, compared to variant 1. The resulting protein (isoform 8) is shorter when it is compared to isoform 1. This variant has also been called 'variant e'.
    Source sequence(s)
    AB073671, AF467005, AL160409, AL450337, AW242451
    Consensus CDS
    CCDS53509.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000363926, OTTHUMP00000019431, ENST00000374794, OTTHUMT00000047530
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 642
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:421500
    Blast Score: 198
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  8. NM_001184792.1NP_001171721.1  partitioning defective 3 homolog isoform 9

    See proteins identical to NP_001171721.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) uses a different splice site, lacks most of the 3' coding region, and contains a different segment for its 3' end, compared to variant 1. The resulting protein (isoform 9) is shorter and has a distinct C-terminus when it is compared to isoform 1. This variant has also been called the 'short variant'.
    Source sequence(s)
    AF196186, AL450337, BE464617, BM796605
    Consensus CDS
    CCDS53516.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000341844, ENST00000340077
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 650
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 194
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  9. NM_001184793.1NP_001171722.1  partitioning defective 3 homolog isoform 10

    See proteins identical to NP_001171722.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) uses three different splice sites, lacks most of the 3' coding region, and contains a different segment for its 3' end, compared to variant 1. The resulting protein (isoform 10) is shorter and has a distinct C-terminus when it is compared to isoform 1.
    Source sequence(s)
    AF332592, AK024668, AK027735, AL450337, BE464617
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000363905, OTTHUMP00000019434, ENST00000374773, OTTHUMT00000047534
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 650
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 194
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  10. NM_001184794.1NP_001171723.1  partitioning defective 3 homolog isoform 11

    See proteins identical to NP_001171723.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) lacks an alternate, in-frame, exon, uses two different splice sites, lacks most of the 3' coding region, and contains a different segment for its 3' end, compared to variant 1. The resulting protein (isoform 11) is shorter and has a distinct C-terminus when it is compared to isoform 1. This variant has also been called 'short variant b'.
    Source sequence(s)
    AF332592, AK024668, AL450337, BE464617
    Consensus CDS
    CCDS53513.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000363908, OTTHUMP00000019427, ENST00000374776, OTTHUMT00000047526
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 651
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 193
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  11. NM_019619.3NP_062565.2  partitioning defective 3 homolog isoform 1

    See proteins identical to NP_062565.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1). This variant has also been called 'variant a'.
    Source sequence(s)
    AA136967, AF467002, AL160409, AL450337, AW242451
    Consensus CDS
    CCDS7178.1
    UniProtKB/Swiss-Prot
    Q8TEW0
    Related
    ENSP00000363921, OTTHUMP00000019428, ENST00000374789, OTTHUMT00000047527
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000010.11 

    Range
    34109560..34815325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006717475.1XP_006717538.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 642
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 198
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  2. XM_005252531.2XP_005252588.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  3. XM_005252528.2XP_005252585.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  4. XM_006717472.1XP_006717535.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 642
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  5. XM_006717478.1XP_006717541.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 643
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:421500
    Blast Score: 197
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  6. XM_006717474.1XP_006717537.1  

    UniProtKB/TrEMBL
    Q5VWV2
    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:421500
    Blast Score: 197
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  7. XM_005252532.2XP_005252589.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 643
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:421500
    Blast Score: 198
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  8. XM_005252530.2XP_005252587.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 644
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 199
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  9. XM_006717473.1XP_006717536.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1107
    Blast Score: 487
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:426505
    Blast Score: 200
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  10. XM_006717471.1XP_006717534.1  

    Conserved Domains (2) summary
    pfam12053
    Location:9114
    Blast Score: 483
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:433512
    Blast Score: 200
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  11. XM_006717476.1XP_006717539.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 652
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 195
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  12. XM_006717477.1XP_006717540.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 651
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 195
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  13. XM_005252535.2XP_005252592.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 651
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 194
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  14. XM_005252534.2XP_005252591.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 650
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 194
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  15. XM_005252536.2XP_005252593.1  

    Conserved Domains (2) summary
    pfam12053
    Location:1146
    Blast Score: 657
    DUF3534; Domain of unknown function (DUF3534)
    cd00992
    Location:465544
    Blast Score: 192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

Alternate HuRef

Genomic

  1. AC_000142.1 

    Range
    34117758..34726488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018921.2 

    Range
    34399927..35105524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)