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Ddx21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [ Mus musculus (house mouse) ]

Gene ID: 56200, updated on 28-May-2016
Official Symbol
Ddx21provided by MGI
Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21provided by MGI
Primary source
MGI:MGI:1860494
See related
Ensembl:ENSMUSG00000020075
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI255159; AL022742; D10Wsu42e; D10Ertd645e
Orthologs
Location:
10 32.43 cM; 10 B4-B5.1
Exon count:
15
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (62580247..62602298, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (62042995..62065046, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene serglycin Neighboring gene KIF1 binding protein Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 Neighboring gene storkhead box 1 Neighboring gene crumbs homolog 1 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (1) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
7SK snRNA binding ISO
Inferred from Sequence Orthology
more info
 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP-dependent RNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
ATP-dependent RNA helicase activity ISO
Inferred from Sequence Orthology
more info
 
RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
RNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
double-stranded RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
rRNA binding ISO
Inferred from Sequence Orthology
more info
 
snoRNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
RNA secondary structure unwinding IBA
Inferred from Biological aspect of Ancestor
more info
 
osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
response to exogenous dsRNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to virus IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
membrane ISO
Inferred from Sequence Orthology
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Preferred Names
nucleolar RNA helicase 2
Names
DEAD box protein 21
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21 (RNA helicase II/Gu)
RH II/Gu
RH-II/Gualpha
gu-alpha
nucleolar RNA helicase Gu
nucleolar RNA helicase II
NP_062426.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019553.2NP_062426.2  nucleolar RNA helicase 2

    See identical proteins and their annotated locations for NP_062426.2

    Status: VALIDATED

    Source sequence(s)
    BC059237, BC060220, CF182162
    Consensus CDS
    CCDS23891.1
    UniProtKB/Swiss-Prot
    Q9JIK5
    UniProtKB/TrEMBL
    Q6PCP0
    Related
    ENSMUSP00000042691, ENSMUST00000045866
    Conserved Domains (5) summary
    PRK01297
    Location:191633
    PRK01297; ATP-dependent RNA helicase RhlB; Provisional
    cd00079
    Location:501610
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:260467
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    cd12936
    Location:689781
    GUCT_RHII_Gualpha_beta; RNA-binding GUCT domain found in vertebrate RNA helicase II/Gualpha (RH-II/Gualpha), RNA helicase II/Gubeta (RH-II/Gubeta) and similar proteins
    pfam15320
    Location:794837
    RAM; mRNA cap methylation, RNMT-activating mini protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    62580247..62602298 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    63683725..63705771 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)