PRKY protein kinase, Y-linked, pseudogene [Homo sapiens] - Gene

Help top of page

Summary

Official Symbol: PRKYprovided by HGNC
Official Full Name: protein kinase, Y-linked, pseudogeneprovided by HGNC
Primary source: HGNC:9444
See related: HPRD:08949; MIM:400008
Gene type: pseudo
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: PRKYP; PRKXP3
Summary: This gene is similar to the protein kinase, X-linked gene in the pseudoautosomal region of the X chromosome. The gene is classified as a transcribed pseudogene because it has lost a coding exon that results in all transcripts being candidates for nonsense-mediated decay (NMD) and unlikely to express a protein. Abnormal recombination between this gene and a related gene on chromosome X is a frequent cause of XX males and XY females. [provided by RefSeq, Jul 2010]

Help top of page

Genomic context

Location :: Yp11.2

Sequence :: Chromosome: Y; NC_000024.9 (7142013..7249588)

See PRKY in Epigenomics, MapViewer

Chromosome Y - NC_000024.9 Genomic Context describing neighboring genes

Help top of page

Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Help top of page

Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of genetic testing. (HuGE Navigator)
Title: Perioperative genomic profiles using structure-specific oligonucleotide probes.

Submit: New GeneRIF Correction

Help top of page

Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

Help top of page

Function	Evidence Code	Pubs
ATP binding	IEA Inferred from Electronic Annotation more info
nucleotide binding	IEA Inferred from Electronic Annotation more info
protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
protein phosphorylation	TAS Traceable Author Statement more info	PubMed

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

NR_028062.1 RNA Sequence

Source sequence(s)

AA767129, AC007284, AC010143, BC074852, Y15801

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000024.9 Reference GRCh37.p5 Primary Assembly

Range

7142013..7249588

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000156.1 Alternate HuRef

Range

4701261..4807158

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_002760.3: Suppressed sequence

Description

NM_002760.3: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.

Help top of page

Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC007284.4	None
genomic	AC010143.3 (47917..79847)	None
genomic	CH471163.1	EAW59124.1
		EAW59125.1
genomic	Y13927.1	CAA74244.1
mRNA	AA767129.1	None
mRNA	AI929361.1	None
mRNA	BC074851.2	AAH74851.1
mRNA	BC074852.2	AAH74852.1
mRNA	BG698237.1	None
mRNA	Y10484.1	CAA71508.1
mRNA	Y10485.1	CAA71509.1
mRNA	Y15801.1	CAA75792.1