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TEX11 testis expressed 11 [ Homo sapiens (human) ]

Gene ID: 56159, updated on 8-May-2016
Official Symbol
TEX11provided by HGNC
Official Full Name
testis expressed 11provided by HGNC
Primary source
HGNC:HGNC:11733
See related
Ensembl:ENSG00000120498 HPRD:02256; MIM:300311; Vega:OTTHUMG00000021782
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TGC1; TSGA3; SPGFX2
Summary
This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs
Location:
Xq13.1
Exon count:
34
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) X NC_000023.11 (70525561..70908717, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (69748790..70128567, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373244 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene DLG3 antisense RNA 1 Neighboring gene discs large MAGUK scaffold protein 3 Neighboring gene coiled-coil domain containing 53 pseudogene Neighboring gene uncharacterized LOC105373245 Neighboring gene solute carrier family 7 member 3 Neighboring gene ribosomal protein S23 pseudogene 8

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
chiasma assembly IEA
Inferred from Electronic Annotation
more info
 
fertilization IEA
Inferred from Electronic Annotation
more info
 
male gonad development IEA
Inferred from Electronic Annotation
more info
 
male meiosis chromosome segregation IEA
Inferred from Electronic Annotation
more info
 
meiotic gene conversion ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
reciprocal meiotic recombination ISS
Inferred from Sequence or Structural Similarity
more info
 
resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 
synaptonemal complex assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
central element IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with synaptonemal complex ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
testis-expressed sequence 11 protein
Names
testis expressed sequence 11

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012574.1 RefSeqGene

    Range
    5001..384778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001003811.1NP_001003811.1  testis-expressed sequence 11 protein isoform 1

    See identical proteins and their annotated locations for NP_001003811.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK057523, BC036016, BG219070, BU929507
    Consensus CDS
    CCDS35323.1
    UniProtKB/Swiss-Prot
    Q8IYF3
    Related
    ENSP00000379226, OTTHUMP00000217425, ENST00000395889, OTTHUMT00000359072
    Conserved Domains (2) summary
    pfam08631
    Location:189444
    SPO22; Meiosis protein SPO22/ZIP4 like
    sd00006
    Location:417451
    TPR; TPR repeat [structural motif]
  2. NM_031276.2NP_112566.2  testis-expressed sequence 11 protein isoform 2

    See identical proteins and their annotated locations for NP_112566.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' region, as compared to variant 1. It uses an upstream in-frame AUG codon and encodes isoform 2 which has a shorter and distinct N-terminus, as compared to isoform 1.
    Source sequence(s)
    AK057391, AK057523, BC036016, BG219070, BU929507
    Consensus CDS
    CCDS43968.1
    UniProtKB/Swiss-Prot
    Q8IYF3
    Related
    ENSP00000363453, OTTHUMP00000023480, ENST00000374333, OTTHUMT00000057083
    Conserved Domains (2) summary
    pfam08631
    Location:174429
    SPO22; Meiosis protein SPO22/ZIP4 like
    sd00006
    Location:402436
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p2 Primary Assembly

    Range
    70525561..70908717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011530994.1XP_011529296.1  

    Conserved Domains (2) summary
    pfam08631
    Location:174429
    SPO22; Meiosis protein SPO22/ZIP4 like
    sd00006
    Location:402436
    TPR; TPR repeat [structural motif]
  2. XM_011530995.1XP_011529297.1  

    Conserved Domains (2) summary
    pfam08631
    Location:13133
    SPO22; Meiosis protein SPO22/ZIP4 like
    sd00006
    Location:106140
    TPR; TPR repeat [structural motif]
  3. XM_011530996.1XP_011529298.1  

    UniProtKB/Swiss-Prot
    Q8IYF3
    Related
    ENSP00000363440, OTTHUMP00000023482, ENST00000374320, OTTHUMT00000057085
    Conserved Domains (2) summary
    pfam08631
    Location:1119
    SPO22; Meiosis protein SPO22/ZIP4 like
    sd00006
    Location:92126
    TPR; TPR repeat [structural motif]

Alternate CHM1_1.1

Genomic

  1. NC_018934.2 Alternate CHM1_1.1

    Range
    69642982..70022944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)