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    dvl1b dishevelled, dsh homolog 1b (Drosophila) [ Danio rerio ]

    Gene ID: 560032, updated on 12-May-2012

    Summary

    Official Symbol
    dvl1bprovided by ZNC
    Official Full Name
    dishevelled, dsh homolog 1b (Drosophila)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-071004-1
    Locus tag
    CH211-15P9.4
    See related
    Ensembl:ENSDARG00000055552; Vega:OTTDARG00000008561
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    dvl1; dvl2l

    Genomic context

    Location :
    chromosome: 11
    Sequence :
    Chromosome: 11; NC_007122.5 (25294330..25361796, complement)
    See dvl1b in MapViewer

    Chromosome 11 - NC_007122.5Genomic Context describing neighboring genes Neighboring gene si:ch211-15p9.2 Neighboring gene NFS1 nitrogen fixation 1 (S. cerevisiae) Neighboring gene matrix-remodelling associated 8a Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 5a

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:286211 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:286211 BioGRID:673849 nkd2a    BioGRID  PubMed Affinity Capture-Western 

    General gene information

    Markers

    Pathways from BioSystems

    • Melanogenesis, organism-specific biosystem (from KEGG)
      Melanogenesis, organism-specific biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • Melanogenesis, conserved biosystem (from KEGG)
      Melanogenesis, conserved biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • Notch signaling pathway, organism-specific biosystem (from KEGG)
      Notch signaling pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, conserved biosystem (from KEGG)
      Notch signaling pathway, conserved biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Wnt Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Wnt Signaling Pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
    • Wnt signaling pathway, organism-specific biosystem (from KEGG)
      Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
    • Wnt signaling pathway, conserved biosystem (from KEGG)
      Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    Rac GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    frizzled binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    axon extension IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    canonical Wnt receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cochlea morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    collateral sprouting IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    convergent extension IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    dendrite morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organismal development IEA
    Inferred from Electronic Annotation
    more info
     
    planar cell polarity pathway involved in neural tube closure IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of transcription, DNA-dependent IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    skeletal muscle acetylcholine-gated channel clustering IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    axon IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    clathrin-coated vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    growth cone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    segment polarity protein dishevelled homolog DVL-1
    Names
    segment polarity protein dishevelled homolog DVL-1
    dishevelled, dsh homolog 1
    dishevelled, dsh homolog 2, like

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044917.1NP_001038382.1  segment polarity protein dishevelled homolog DVL-1

      Status: PROVISIONAL

      Source sequence(s)
      BX001056
      UniProtKB/TrEMBL
      Q1LYR0
      Related
      ENSDARP00000094527, OTTDARP00000008455, ENSDART00000103752, OTTDART00000009827
      Conserved Domains (4) summary
      cd00992
      Location:243330
      Blast Score: 185
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:386469
      Blast Score: 409
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam12316
      Location:473697
      Blast Score: 318
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
      cl02426
      Location:185
      Blast Score: 369
      DIX; DIX domain

    RefSeqs of Annotated Genomes: Build 5.1

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Zv9 Primary Assembly

    Genomic

    1. NC_007122.5 Reference Zv9 Primary Assembly

      Range
      25294330..25361796, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BX001056.6 CAK04197.1
    mRNA BC171461.1 AAI71461.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1LYR0 GenPept UniProtKB/TrEMBL:Q1LYR0

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