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    Cpxm2 carboxypeptidase X 2 (M14 family) [ Mus musculus (house mouse) ]

    Gene ID: 55987, updated on 26-Feb-2013
    Official Symbol
    Cpxm2provided by MGI
    Official Full Name
    carboxypeptidase X 2 (M14 family)provided by MGI
    Primary source
    MGI:1926006
    See related
    Ensembl:ENSMUSG00000030862; Vega:OTTMUSG00000025187
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cpx2; CPX-2; 4632435C11Rik
    Location :
    7; 7 F4
    Sequence :
    Chromosome: 7; NC_000073.6 (132042810..132154741, complement)
    See Cpxm2 in Epigenomics, MapViewer

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene U1 small nuclear ribonucleoprotein 1C pseudogene Neighboring gene G protein-coupled receptor 26 Neighboring gene carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 Neighboring gene predicted gene, 19463 Neighboring gene predicted gene 10584 Neighboring gene high mobility group box 1 pseudogene

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068.
    3. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862.
    4. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416.
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073.

    See all (15) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NOT carboxypeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT proteolysis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
    		  
    Preferred Names
    inactive carboxypeptidase-like protein X2
    Names
    inactive carboxypeptidase-like protein X2
    carboxypeptidase X2
    metallocarboxypeptidase 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018867.5 → NP_061355.3  inactive carboxypeptidase-like protein X2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC100735, AK019509, BB027417
      Consensus CDS
      CCDS21921.1
      UniProtKB/Swiss-Prot
      Q9D2L5
      Related
      ENSMUSP00000033149, OTTMUSP00000030523, ENSMUST00000033149, OTTMUST00000062013
      Conserved Domains (4) summary
      cd00057
      Location:145 – 300
      Blast Score: 428
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      smart00231
      Location:146 – 301
      Blast Score: 355
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      cd03869
      Location:322 – 647
      Blast Score: 1636
      M14_CPX_like; Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase X subgroup
      cd11308
      Location:651 – 726
      Blast Score: 339
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p1 C57BL/6J

      Range
      132042810..132154741, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000029.1 Alternate Mm_Celera

      Range
      131849272..131959301, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01066740.1 None
    genomic AAHY01066741.1 None
    genomic AAHY01066742.1 None
    genomic AAHY01066743.1 (20971..35876) None
    genomic AC100735.15 (58581..170507) None
    genomic CH466531.1 EDL17722.1 mixed
      EDL17723.1 mixed
    mRNA AF017639.1 AAC04670.1
    mRNA AK019509.1 BAB31768.1 C57BL/6J
    mRNA AK038874.1 None C57BL/6J
    mRNA BB027417.1 None C57BL/6J
    mRNA BC021444.1 AAH21444.1 CZECHII
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D2L5.1 GenPept UniProtKB/Swiss-Prot:Q9D2L5

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioProjects
        BioProjects related to a gene
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • EST
        Link to related EST entry
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

      General information

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