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Impa1 inositol (myo)-1(or 4)-monophosphatase 1 [ Mus musculus (house mouse) ]

Gene ID: 55980, updated on 8-May-2016
Official Symbol
Impa1provided by MGI
Official Full Name
inositol (myo)-1(or 4)-monophosphatase 1provided by MGI
Primary source
MGI:MGI:1933158
See related
Ensembl:ENSMUSG00000027531
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI325909; 2610002K09Rik; 2900059K10Rik
Orthologs
Location:
3; 3 A1
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (10313540..10331439, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (10313540..10331439, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene fatty acid binding protein 4, adipocyte Neighboring gene fatty acid binding protein 12 Neighboring gene uncharacterized LOC102636393 Neighboring gene solute carrier family 10 (sodium/bile acid cotransporter family), member 5 Neighboring gene zinc finger, AN1-type domain 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
inositol monophosphate 1-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
inositol monophosphate 1-phosphatase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
inositol monophosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
inositol monophosphate 4-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
inositol monophosphate phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
lithium ion binding ISO
Inferred from Sequence Orthology
more info
 
magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
manganese ion binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
inositol metabolic process TAS
Traceable Author Statement
more info
PubMed 
inositol phosphate dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
inositol phosphate dephosphorylation ISO
Inferred from Sequence Orthology
more info
PubMed 
phosphate-containing compound metabolic process ISO
Inferred from Sequence Orthology
more info
 
phosphatidylinositol biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
phosphatidylinositol phosphorylation IEA
Inferred from Electronic Annotation
more info
 
signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
signal transduction ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
axon ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
inositol monophosphatase 1
Names
D-galactose 1-phosphate phosphatase
IMP 1
IMPase 1
inositol-1(or 4)-monophosphatase 1
lithium-sensitive myo-inositol monophosphatase A1
NP_061352.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310433.1NP_001297362.1  inositol monophosphatase 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, resulting in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK145472, AK152774, BY283562
    Consensus CDS
    CCDS79884.1
    UniProtKB/TrEMBL
    A0A0A6YW07, Q924B0
    Conserved Domains (1) summary
    cd01639
    Location:8164
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...
  2. NM_018864.6NP_061352.2  inositol monophosphatase 1 isoform 1

    See identical proteins and their annotated locations for NP_061352.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK145472, AK152774, BY283562
    Consensus CDS
    CCDS17240.1
    UniProtKB/TrEMBL
    Q924B0
    Related
    ENSMUSP00000068174, OTTMUSP00000034806, ENSMUST00000065938, OTTMUST00000068723
    Conserved Domains (1) summary
    cd01639
    Location:8254
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    10313540..10331439 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530079.2XP_006530142.1  

    Related
    ENSMUSP00000141345, OTTMUSP00000069788, ENSMUST00000191670, OTTMUST00000130084
    Conserved Domains (1) summary
    cd01639
    Location:8164
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...
  2. XM_006530078.2XP_006530141.1  

    Conserved Domains (1) summary
    cd01639
    Location:61217
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...
  3. XM_006530077.2XP_006530140.1  

    Conserved Domains (1) summary
    cd01639
    Location:61307
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    10347693..10365549 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)