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abtb2a ankyrin repeat and BTB (POZ) domain containing 2a [ Danio rerio (zebrafish) ]

Gene ID: 559451, updated on 27-Mar-2024

Summary

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Official Symbol
abtb2aprovided by ZNC
Official Full Name
ankyrin repeat and BTB (POZ) domain containing 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-100422-13
See related
Ensembl:ENSDARG00000059751 AllianceGenome:ZFIN:ZDB-GENE-100422-13
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
abtb2
Summary
Predicted to enable protein heterodimerization activity. Orthologous to human ABTB2 (ankyrin repeat and BTB domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (49272322..49318816)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (48999517..49045973)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:ch211-288d18.1 Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 4b Neighboring gene si:busm1-180g5.6 Neighboring gene BR serine/threonine kinase 2b Neighboring gene tumor susceptibility 101b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Molecular evolution and functional divergence of zebrafish (Danio rerio) cryptochrome genes. Liu C, et al. Sci Rep, 2015 Jan 29. PMID 25630924, Free PMC Article
  2. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ankyrin repeat and BTB/POZ domain-containing protein 2
Names
ankyrin repeat and BTB (POZ) domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    49272322..49318816
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_682789.7 → XP_687881.4  ankyrin repeat and BTB/POZ domain-containing protein 2

    UniProtKB/TrEMBL
    A0A8N7UV41, E7F2F4
    Related
    ENSDARP00000077824.5, ENSDART00000083389.7
    Conserved Domains (8) summary
    smart00225
    Location:834 → 935
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cd00204
    Location:505 → 655
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14821
    Location:935 → 986
    SPOP_C_like; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
    pfam00651
    Location:825 → 928
    BTB; BTB/POZ domain
    pfam12796
    Location:515 → 625
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:598 → 655
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:513 → 554
    ANK; ANK repeat [structural motif]
    cl23907
    Location:187 → 235
    H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...
Nucleotide Protein
Heading Accession and Version

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