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IMPACT impact RWD domain protein [ Homo sapiens (human) ]

Gene ID: 55364, updated on 8-May-2016
Official Symbol
IMPACTprovided by HGNC
Official Full Name
impact RWD domain proteinprovided by HGNC
Primary source
HGNC:HGNC:20387
See related
Ensembl:ENSG00000154059 HPRD:13739; MIM:615319; Vega:OTTHUMG00000131943
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RWDD5
Orthologs
Location:
18q11.2-q12.1
Exon count:
11
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 18 NC_000018.10 (24426645..24453531)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (22006609..22033499)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein like 1A Neighboring gene uncharacterized LOC105372025 Neighboring gene microRNA 320c-2 Neighboring gene uncharacterized LOC105372026 Neighboring gene histamine receptor H4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC33718

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
ribosome binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
cellular response to UV-C ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to acidic pH ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to amino acid starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to benomyl ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to glucose starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to hydrogen peroxide ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to leucine starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of cell death ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of protein autophosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of protein complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription from RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription from RNA polymerase II promoter in response to stress ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron projection extension ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of translational initiation in response to starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of eIF2 alpha phosphorylation by amino acid starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
polysome ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
protein IMPACT
Names
Impact homolog
RWD domain containing 5
imprinted and ancient gene protein homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018439.3NP_060909.1  protein IMPACT

    See identical proteins and their annotated locations for NP_060909.1

    Status: VALIDATED

    Source sequence(s)
    AB026264, AK292533, BP384088
    Consensus CDS
    CCDS11886.1
    UniProtKB/Swiss-Prot
    Q9P2X3
    UniProtKB/TrEMBL
    A0A024RC24
    Related
    ENSP00000284202, OTTHUMP00000162779, ENST00000284202, OTTHUMT00000254901
    Conserved Domains (2) summary
    smart00591
    Location:15115
    RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain
    pfam01205
    Location:181289
    UPF0029; Uncharacterized protein family UPF0029

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p2 Primary Assembly

    Range
    24426645..24453531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018929.2 Alternate CHM1_1.1

    Range
    21933622..21960504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)