Display Settings:

Format

Send to:

Choose Destination

    SYNJ2BP synaptojanin 2 binding protein [ Homo sapiens ]

    Gene ID: 55333, updated on 8-Jan-2012

    Summary

    Official Symbol
    SYNJ2BPprovided by HGNC
    Official Full Name
    synaptojanin 2 binding proteinprovided by HGNC
    Primary source
    HGNC:18955
    See related
    Ensembl:ENSG00000213463; HPRD:15455; MIM:609411; Vega:OTTHUMG00000171240
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ARIP2; OMP25

    Genomic context

    Location :
    14q24.2
    Sequence :
    Chromosome: 14; NC_000014.8 (70833213..70883807, complement)
    See SYNJ2BP in Epigenomics, MapViewer

    Chromosome 14 - NC_000014.8Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase domain 21 pseudogene 1 Neighboring gene SYNJ2BP-COX16 readthrough Neighboring gene COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) Neighboring gene ADAM metallopeptidase domain 21 Neighboring gene metalloproteinase-disintegrin 1-2 pseudogene

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    P57105 P60709 ACTB    HPRD  PubMed  
    P57105 P27037 ACVR2A    HPRD  PubMed  
    P57105 Q13705 ACVR2B    HPRD  PubMed  
    P57105 Q07954 LRP1    HPRD  PubMed  
    P57105 P98164 LRP2    HPRD  PubMed  
    P57105 Q15311 RALBP1    HPRD  PubMed  
    P57105 O15056 SYNJ2    HPRD  PubMed  
    BioGRID:120614 BioGRID:106607 ACVR2A    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:120614 BioGRID:106608 ACVR2B    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:120614 BioGRID:110215 LRP1    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:120614 BioGRID:110216 LRP2    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:120614 BioGRID:113579 LRP8    BioGRID  PubMed Two-hybrid 
    BioGRID:120614 BioGRID:116131 RALBP1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:120614 BioGRID:114391 SYNJ2    BioGRID  PubMed Reconstituted Complex; Two-hybrid 

    General gene information

    Markers

    Readthrough SYNJ2BP-COX16

    Readthrough gene: SYNJ2BP-COX16, Included gene: COX16

    Homology

    Clone Names

    • FLJ11271, FLJ41973

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein C-terminus binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    intracellular distribution of mitochondria IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral to mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    synaptojanin-2-binding protein
    Names
    synaptojanin-2-binding protein
    activin receptor interacting protein 5
    mitochondrial outer membrane protein 25

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018373.2NP_060843.2  synaptojanin-2-binding protein

      Status: VALIDATED

      Source sequence(s)
      AL356804, BC007704, BP195583, BQ775922
      Consensus CDS
      CCDS9803.1
      UniProtKB/Swiss-Prot
      P57105
      Related
      ENSP00000256366, OTTHUMP00000245525, ENST00000256366, OTTHUMT00000412472
      Conserved Domains (1) summary
      cd00992
      Location:1397
      Blast Score: 183
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000014.8 Reference GRCh37.p5 Primary Assembly

      Range
      70833213..70883807, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000146.1 Alternate HuRef

      Range
      51001739..51052566, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AL356804.4 (110253..160269) None
    genomic CH471061.1 EAW81032.1
      EAW81033.1
    mRNA AK002133.1 BAA92098.1
    mRNA AK123967.1 None
    mRNA AK311719.1 None
    mRNA AY534623.1 AAT01566.1
    mRNA BC007704.2 AAH07704.1
    mRNA BP195583.1 None
    mRNA BQ775922.1 None
    Protein Accession Links
    GenePept Link UniProtKB Link
    P57105.2 GenPept UniProtKB/Swiss-Prot:P57105

      Supplemental Content

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...