These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_012392.3 → NP_036524.1 peflin
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein.
- Source sequence(s)
-
AC114488, BC012561, CA307778, DC301714
- Consensus CDS
-
CCDS345.1
- UniProtKB/Swiss-Prot
-
Q9UBV8
- Related
- ENSP00000362807, OTTHUMP00000003953, ENST00000373703, OTTHUMT00000011046
- Conserved Domains (3) summary
-
- cd00051
Location:123 – 181
Blast Score: 111
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- COG5126
Location:183 – 281
Blast Score: 112
- FRQ1; Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]
- pfam13499
Location:124 – 180
Blast Score: 101
- EF_hand_5; EF-hand domain pair
RNA
-
NR_033686.1 RNA Sequence
- Description
- Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC114488, BC012561, BG546473, CA307778, DC301714
-
NR_033688.1 RNA Sequence
- Description
- Transcript Variant: This variant (3) contains an alternate 5' exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC114488, BC012561, BI826532, CA307778, DB024828
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000001.10 Reference GRCh37.p5 Primary Assembly
- Range
- 32095463..32110838, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000133.1 Alternate HuRef
- Range
- 30212972..30228346, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)